中国云南省采集的蝙蝠感染冠状病毒的不同流行率和风险因素

IF 4.1 2区医学 Q1 INFECTIOUS DISEASES

One Health Pub Date : 2024-10-28 DOI:10.1016/j.onehlt.2024.100923

Ruiya Li , Alexander Tendu , Yakhouba Kane , Victor Omondi , Jiaxu Ying , Lingjing Mao , Shiman Xu , Rong Xu , Xing Chen , Yanhua Chen , Stéphane Descorps-Declère , Kathrina Mae Bienes , Meriem Fassatoui , Alice C. Hughes , Nicolas Berthet , Gary Wong

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引用次数: 0

摘要

冠状病毒（CoVs）对全球人类健康构成威胁，严重急性呼吸系统综合症（SARS）、中东呼吸系统综合症（MERS）和 COVID-19 大流行就是突出的例子。大湄公河次区域（GMS）的蝙蝠是 CoVs 的重要天然贮藏地。在此，我们报告了云南省内不同生物和生态变量下蝙蝠中 CoVs 的不同流行率。我们还显示了CoV在蝙蝠个体中的共存，并确定了与SARS相关的CoV的另一种假定宿主，其传播能力高于其他已知宿主。值得注意的是，通过泛CoV检测和Illumina测序，我们在马蹄蝠（鼻蝠科）和中国水蓑衣蝠（Myotis laniger）中发现了11种SARS相关冠状病毒（SARSr-CoVs）。我们的研究结果有助于了解CoV在自然界分布和循环的基本特征，以及 "一个健康 "框架下的人畜共患外溢风险。

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Differential prevalence and risk factors for infection with coronaviruses in bats collected from Yunnan Province, China

Coronaviruses (CoVs) pose a threat to human health globally, as highlighted by severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the COVID-19 pandemic. Bats from the Greater Mekong Subregion (GMS) are an important natural reservoir for CoVs. Here we report the differential prevalence of CoVs in bats within Yunnan Province across biological and ecological variables. We also show the coexistence of CoVs in individual bats and identify an additional putative host for SARS-related CoV, with higher dispersal capacity than other known hosts. Notably, 11 SARS-related coronaviruses (SARSr-CoVs) were discovered in horseshoe bats (family Rhinolophidae) and a Chinese water myotis bat (Myotis laniger) by pan-CoV detection and Illumina sequencing. Our findings facilitate an understanding of the fundamental features of the distribution and circulation of CoVs in nature as well as zoonotic spillover risk in the One health framework.

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来源期刊

One Health Medicine-Infectious Diseases

CiteScore

8.10

自引率

4.00%

发文量

审稿时长

18 weeks

期刊介绍： One Health - a Gold Open Access journal. The mission of One Health is to provide a platform for rapid communication of high quality scientific knowledge on inter- and intra-species pathogen transmission, bringing together leading experts in virology, bacteriology, parasitology, mycology, vectors and vector-borne diseases, tropical health, veterinary sciences, pathology, immunology, food safety, mathematical modelling, epidemiology, public health research and emergency preparedness. As a Gold Open Access journal, a fee is payable on acceptance of the paper. Please see the Guide for Authors for more information. Submissions to the following categories are welcome: Virology, Bacteriology, Parasitology, Mycology, Vectors and vector-borne diseases, Co-infections and co-morbidities, Disease spatial surveillance, Modelling, Tropical Health, Discovery, Ecosystem Health, Public Health.