Robinson Ramírez-Vélez, Hugo Alejandro Carrillo-Arango, Miguel Alejandro Atencio-Osorio, Carlos Alejandro López-Álban, Juan Carlos Calderon-González, David Morales-Álamo, Mikel Izquierdo, María Correa-Rodríguez
{"title":"脂肪过多的成年人在口服 75 克葡萄糖后进行急性短跑间歇训练时，全身代谢反应无性别差异。","authors":"Robinson Ramírez-Vélez, Hugo Alejandro Carrillo-Arango, Miguel Alejandro Atencio-Osorio, Carlos Alejandro López-Álban, Juan Carlos Calderon-González, David Morales-Álamo, Mikel Izquierdo, María Correa-Rodríguez","doi":"10.1016/j.clnesp.2024.11.005","DOIUrl":null,"url":null,"abstract":"<p><strong>Background & aims: </strong>Research exploring sex-based variations in responses to acute sprint interval training (SIT) remains limited. This study aimed to examine the impact of biological sex on the systemic metabolic response to SIT. We hypothesized that acute metabolic responses to SIT would differ between males and females.</p><p><strong>Methods: </strong>Sedentary adults (15 males; 14 females) with excess adiposity (defined as body fat > 30%) were matched for age (32.8 ± 7.5 vs. 29.5 ± 6.5 years) and body fat mass (33.0 ± 6.9 vs. 33.2 ± 6.8%). Following a 75-g glucose load, participants were randomly allocated to either a control (resting) or SIT trial (8 × 30 s of \"all-out\" cycling at a resistance of 0.075% W kg<sup>-1</sup> of muscle mass, interspersed with 1 min of recovery). Parameters assessed included respiratory quotient (RQ), resting energy expenditure (REE), substrate utilization rates (fat and carbohydrate), total energy output, and blood lactate and glucose levels. These were collected during fasting and at 60, 120, and 240 minutes post-glucose load, with the area under the curve (AUC) calculated for both trials.</p><p><strong>Results: </strong>An interaction was observed between sex × time (P = 0.012) and trial (P < 0.001) for RQ over time; however, there was no significant interaction between sex and trial (P = 0.818). Males exhibited higher mean REE values than females in both conditions. Nevertheless, AUC analysis showed no significant interaction between sex and trial (P = 0.562). A significant trial × time relationship was found for fat and carbohydrate percentage contributions (P < 0.001). Post-SIT, AUCs for fat contribution (g min<sup>-1</sup> and mg kg<sup>-</sup>1 min<sup>-1</sup>) to energy expenditure increased in both sexes compared with resting (P < 0.05), with differences noted among trials over time (P < 0.001). Blood lactate levels also increased similarly post-SIT in both sexes (P < 0.05), without a significant sex × trial interaction (AUC, P = 0.798).</p><p><strong>Conclusions: </strong>These data demonstrate that exercise differed between the sexes and did not support the premise that acute metabolic responses to SIT would vary between males and females.</p>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"No sex differences in systemic metabolic responses to acute sprint interval training performed after an oral 75-g glucose load in adults with excess adiposity.\",\"authors\":\"Robinson Ramírez-Vélez, Hugo Alejandro Carrillo-Arango, Miguel Alejandro Atencio-Osorio, Carlos Alejandro López-Álban, Juan Carlos Calderon-González, David Morales-Álamo, Mikel Izquierdo, María Correa-Rodríguez\",\"doi\":\"10.1016/j.clnesp.2024.11.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background & aims: </strong>Research exploring sex-based variations in responses to acute sprint interval training (SIT) remains limited. This study aimed to examine the impact of biological sex on the systemic metabolic response to SIT. We hypothesized that acute metabolic responses to SIT would differ between males and females.</p><p><strong>Methods: </strong>Sedentary adults (15 males; 14 females) with excess adiposity (defined as body fat > 30%) were matched for age (32.8 ± 7.5 vs. 29.5 ± 6.5 years) and body fat mass (33.0 ± 6.9 vs. 33.2 ± 6.8%). Following a 75-g glucose load, participants were randomly allocated to either a control (resting) or SIT trial (8 × 30 s of \\\"all-out\\\" cycling at a resistance of 0.075% W kg<sup>-1</sup> of muscle mass, interspersed with 1 min of recovery). Parameters assessed included respiratory quotient (RQ), resting energy expenditure (REE), substrate utilization rates (fat and carbohydrate), total energy output, and blood lactate and glucose levels. These were collected during fasting and at 60, 120, and 240 minutes post-glucose load, with the area under the curve (AUC) calculated for both trials.</p><p><strong>Results: </strong>An interaction was observed between sex × time (P = 0.012) and trial (P < 0.001) for RQ over time; however, there was no significant interaction between sex and trial (P = 0.818). Males exhibited higher mean REE values than females in both conditions. Nevertheless, AUC analysis showed no significant interaction between sex and trial (P = 0.562). A significant trial × time relationship was found for fat and carbohydrate percentage contributions (P < 0.001). Post-SIT, AUCs for fat contribution (g min<sup>-1</sup> and mg kg<sup>-</sup>1 min<sup>-1</sup>) to energy expenditure increased in both sexes compared with resting (P < 0.05), with differences noted among trials over time (P < 0.001). Blood lactate levels also increased similarly post-SIT in both sexes (P < 0.05), without a significant sex × trial interaction (AUC, P = 0.798).</p><p><strong>Conclusions: </strong>These data demonstrate that exercise differed between the sexes and did not support the premise that acute metabolic responses to SIT would vary between males and females.</p>\",\"PeriodicalId\":10352,\"journal\":{\"name\":\"Clinical nutrition ESPEN\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical nutrition ESPEN\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.clnesp.2024.11.005\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition ESPEN","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.clnesp.2024.11.005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
No sex differences in systemic metabolic responses to acute sprint interval training performed after an oral 75-g glucose load in adults with excess adiposity.
Background & aims: Research exploring sex-based variations in responses to acute sprint interval training (SIT) remains limited. This study aimed to examine the impact of biological sex on the systemic metabolic response to SIT. We hypothesized that acute metabolic responses to SIT would differ between males and females.
Methods: Sedentary adults (15 males; 14 females) with excess adiposity (defined as body fat > 30%) were matched for age (32.8 ± 7.5 vs. 29.5 ± 6.5 years) and body fat mass (33.0 ± 6.9 vs. 33.2 ± 6.8%). Following a 75-g glucose load, participants were randomly allocated to either a control (resting) or SIT trial (8 × 30 s of "all-out" cycling at a resistance of 0.075% W kg-1 of muscle mass, interspersed with 1 min of recovery). Parameters assessed included respiratory quotient (RQ), resting energy expenditure (REE), substrate utilization rates (fat and carbohydrate), total energy output, and blood lactate and glucose levels. These were collected during fasting and at 60, 120, and 240 minutes post-glucose load, with the area under the curve (AUC) calculated for both trials.
Results: An interaction was observed between sex × time (P = 0.012) and trial (P < 0.001) for RQ over time; however, there was no significant interaction between sex and trial (P = 0.818). Males exhibited higher mean REE values than females in both conditions. Nevertheless, AUC analysis showed no significant interaction between sex and trial (P = 0.562). A significant trial × time relationship was found for fat and carbohydrate percentage contributions (P < 0.001). Post-SIT, AUCs for fat contribution (g min-1 and mg kg-1 min-1) to energy expenditure increased in both sexes compared with resting (P < 0.05), with differences noted among trials over time (P < 0.001). Blood lactate levels also increased similarly post-SIT in both sexes (P < 0.05), without a significant sex × trial interaction (AUC, P = 0.798).
Conclusions: These data demonstrate that exercise differed between the sexes and did not support the premise that acute metabolic responses to SIT would vary between males and females.
期刊介绍：
Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
