产前皮肤细胞图谱揭示了巨噬细胞在免疫之外的作用。

IF 3.2 4区医学 Q3 CELL BIOLOGY

Immunology & Cell Biology Pub Date : 2024-11-17 DOI:10.1111/imcb.12837

Céline Pattaroni

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引用次数: 0

摘要

在这篇文章中，我们讨论了 Gopee 等人最近发表的一项研究，他们揭示了巨噬细胞在人类产前皮肤发育中的惊人作用，远远超出了其传统的免疫功能。通过构建全面的人类产前皮肤多组学单细胞图谱，他们证明了先天性免疫细胞在毛囊形成、无疤痕伤口愈合和神经血管发育中发挥着关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Prenatal Skin Cell Atlas reveals macrophages' role beyond immunity.

In this article, we discuss a recently published study by Gopee et al., who have unveiled a surprising role for macrophages in human prenatal skin development, extending far beyond their traditional immune function. By constructing a comprehensive multi-omics single-cell atlas of human prenatal skin, they demonstrate that innate immune cells play a key role in hair follicle formation, scarless wound healing and neurovascular development.

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来源期刊

Immunology & Cell Biology 医学-免疫学

CiteScore

7.50

自引率

2.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The Australasian Society for Immunology Incorporated (ASI) was created by the amalgamation in 1991 of the Australian Society for Immunology, formed in 1970, and the New Zealand Society for Immunology, formed in 1975. The aim of the Society is to encourage and support the discipline of immunology in the Australasian region. It is a broadly based Society, embracing clinical and experimental, cellular and molecular immunology in humans and animals. The Society provides a network for the exchange of information and for collaboration within Australia, New Zealand and overseas. ASI members have been prominent in advancing biological and medical research worldwide. We seek to encourage the study of immunology in Australia and New Zealand and are active in introducing young scientists to the discipline.