日本自身免疫性疾病和风湿性疾病患者接受 COVID-19 疫苗加强剂量的相关因素:单中心横断面调查

IF 1.8 4区 医学 Q3 RHEUMATOLOGY
Riki Kurokawa, Sachiko Ohde, Satoshi Kawaai, Hiromichi Tamaki
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引用次数: 0

摘要

研究目的我们研究了日本自身免疫性疾病和风湿性疾病(ARD)患者接受或犹豫接种2019年冠状病毒病(COVID-19)疫苗的现状及相关因素:方法:我们对2023年10月1日至11月30日到圣路加国际医院免疫风湿病中心就诊的ARD门诊患者进行了一次单中心横断面调查。我们调查了患者特征、COVID-19疫苗接种相关状况、决策偏好、健康相关状况以及与接受或犹豫是否接种COVID-19疫苗加强剂相关的独立因素:共有 241 名患者参与了分析,其中 198 名患者(82.2%)接种了加强剂,43 名患者(17.8%)未接种。年龄较大(调整后的几率比 [aOR] = 0.43,95% CI:0.19,0.95,P = 0.037)、患有类风湿性关节炎(RA)(aOR = 0.41,95% CI:0.19,0.92,P = 0.030)和有医生推荐接种疫苗(aOR = 0.47,95% CI:0.23,0.95,P = 0.035)与接受加强剂接种有独立关联。对加强剂量犹豫不决的主要原因是担心不良反应和长期安全性:我们的研究结果可帮助医生指导ARD患者接受COVID-19疫苗加强剂量,以促进患者做出适当的决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors related to acceptance of COVID-19 vaccine booster doses among patients with autoimmune and rheumatic diseases in Japan: A single-center cross-sectional survey.

Objectives: We studied the current state and factors associated with the acceptance or hesitancy of booster doses of the coronavirus disease 2019 (COVID-19) vaccine among patients with autoimmune and rheumatic diseases (ARDs) in Japan.

Methods: A single-center cross-sectional survey was conducted among outpatients with ARDs who visited the Immuno-Rheumatology Center at St. Luke's International Hospital from 1 October to 30 November in 2023. We investigated patient characteristics, COVID-19 vaccination-related status, decision-making preferences, health-related status and independent factors associated with the acceptance or hesitancy of booster doses of the COVID-19 vaccine.

Results: A total of 241 patients were included in the analyses, and 198 patients (82.2%) received booster doses while 43 (17.8%) did not. Older age (adjusted odds ratio [aOR] = 0.43, 95% CI: 0.19, 0.95, P = 0.037), having rheumatoid arthritis (RA) (aOR = 0.41, 95% CI: 0.19, 0.92, P = 0.030) and having a physician recommend receiving the vaccine (aOR = 0.47, 95% CI: 0.23, 0.95, P = 0.035) were independently associated with receiving booster doses. The main reasons for hesitancy regarding booster doses were concerns about adverse reactions and long-term safety.

Conclusion: Our findings could help physicians counsel patients with ARDs regarding their acceptance of COVID-19 vaccine booster doses to promote appropriate decision-making.

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来源期刊
Modern Rheumatology
Modern Rheumatology RHEUMATOLOGY-
CiteScore
4.90
自引率
9.10%
发文量
146
审稿时长
1.5 months
期刊介绍: Modern Rheumatology publishes original papers in English on research pertinent to rheumatology and associated areas such as pathology, physiology, clinical immunology, microbiology, biochemistry, experimental animal models, pharmacology, and orthopedic surgery. Occasional reviews of topics which may be of wide interest to the readership will be accepted. In addition, concise papers of special scientific importance that represent definitive and original studies will be considered. Modern Rheumatology is currently indexed in Science Citation Index Expanded (SciSearch), Journal Citation Reports/Science Edition, PubMed/Medline, SCOPUS, EMBASE, Chemical Abstracts Service (CAS), Google Scholar, EBSCO, CSA, Academic OneFile, Current Abstracts, Elsevier Biobase, Gale, Health Reference Center Academic, OCLC, SCImago, Summon by Serial Solutions
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