Alice Betti, Claudio Ongaro, Barbara Zardin, Jessika Bertacchini, Nadia Tagliaferri, Vincenzina Siciliani, Leonardo Orazi, Massimo Borghi
{"title":"评估微流体中基于激光的微细加工:实验与计算试验","authors":"Alice Betti, Claudio Ongaro, Barbara Zardin, Jessika Bertacchini, Nadia Tagliaferri, Vincenzina Siciliani, Leonardo Orazi, Massimo Borghi","doi":"10.1002/adem.202401105","DOIUrl":null,"url":null,"abstract":"<p>\nThe aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser-etched glass and pre-cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine-tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis.</p>","PeriodicalId":7275,"journal":{"name":"Advanced Engineering Materials","volume":"26 21","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adem.202401105","citationCount":"0","resultStr":"{\"title\":\"Evaluating Laser-Based Microfabrication in Microfluidics: An Experimental and Computational Trial\",\"authors\":\"Alice Betti, Claudio Ongaro, Barbara Zardin, Jessika Bertacchini, Nadia Tagliaferri, Vincenzina Siciliani, Leonardo Orazi, Massimo Borghi\",\"doi\":\"10.1002/adem.202401105\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>\\nThe aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser-etched glass and pre-cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine-tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis.</p>\",\"PeriodicalId\":7275,\"journal\":{\"name\":\"Advanced Engineering Materials\",\"volume\":\"26 21\",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2024-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adem.202401105\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Engineering Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/adem.202401105\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Engineering Materials","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adem.202401105","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
这项研究的目的是验证一种新的微流体设备原型制作方法,该方法可与广泛使用的聚二甲基硅氧烷软光刻法相媲美。这种替代方法使用激光蚀刻玻璃和预固化硅胶作为主要材料。我们选择了一种双重方法进行验证,测试科学文献中众所周知的混合装置原型。具体来说,重点是评估流经该装置的两种流体的混合效率(ME)。在对制造过程进行微调后,对 ME 进行了实验评估,并将结果与三维计算流体动力学分析进行了比较。
Evaluating Laser-Based Microfabrication in Microfluidics: An Experimental and Computational Trial
The aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser-etched glass and pre-cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine-tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis.
期刊介绍:
Advanced Engineering Materials is the membership journal of three leading European Materials Societies
- German Materials Society/DGM,
- French Materials Society/SF2M,
- Swiss Materials Federation/SVMT.