法国产后两个月妇女百日咳疫苗接种率及相关因素，2021 年全国围产期调查。

IF 4.5 3区医学 Q2 IMMUNOLOGY

Vaccine Pub Date : 2024-11-08 DOI:10.1016/j.vaccine.2024.126502

Lisa Dilange , Fatima Ait El Belghiti , Virginie Demiguel , Olivia Anselem , Nolwenn Regnault , Camille Le Ray , Isabelle Parent Du-Châtelet , Sophie Vaux , ENP-2021 Study Group and ENP-DROM 2021 Study Group

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引用次数: 0

摘要

背景：为年轻母亲接种百日咳疫苗旨在通过破茧保护新生儿。我们估算了2021年法国产后两个月妇女的百日咳疫苗接种覆盖率（VC），以及产后头两个月接种疫苗的妇女比例；并对相关决定因素进行了研究：我们使用了在法国本土（ENP 2021）和法国海外领地（ENP-DROM 2021）进行的 2021 年全国围产期调查的数据。采用多变量泊松回归研究了以下决定因素：年龄、教育水平、家庭月收入、社会职业状况、出生国家、奇偶数、监测妊娠的卫生专业人员、孕期流感疫苗接种、居住地区、产前护理咨询、有医疗保险、有伴侣和有慢性病。结果已加权：研究样本包括 7999 名妇女。产后两个月的百日咳 VC 估计值为 66.8%（95 %CI [65.5-68.0]）。i) 失业妇女（与行政/经理、中级和高级知识专业人员相比）、ii) 低收入妇女（与高收入妇女相比）和 iii) 有两个或两个以上孩子的妇女（与初产妇相比）的 VC 明显较低。i) 在法国出生的妇女，ii) 在怀孕期间接种过流感疫苗的妇女，iii) 接受过私人助产士产前护理的妇女，iv) 接受过更多产前咨询的妇女，接种流感疫苗的比例明显更高。产后两个月内接种百日咳疫苗的妇女比例（33.4% [31.7-35.9]）在以下人群中明显较低：i) 低收入妇女；ii) 失业妇女；iii) 有医疗保险的妇女；iv) 多胞胎妇女。在怀孕期间接种过流感疫苗的妇女中，这一比例明显更高：2021 年，产后两个月的妇女百日咳疫苗接种率不足，且存在社会和地区健康不平等现象。法国建议自 2022 年起为孕妇接种疫苗。对这一新建议的影响进行监测研究至关重要。

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Pertussis vaccination coverage in women at two months postpartum and associated factors in France, National Perinatal Survey 2021

Background

Pertussis vaccination in young mothers aims to protect neonates through cocooning. We estimated pertussis vaccination coverage (VC) in women at two months postpartum in France in 2021, and the proportion of women who got vaccinated in the first two months postpartum; associated determinants were studied.

Methods

We used data from the 2021 National Perinatal Surveys conducted in metropolitan France (ENP 2021) and French overseas territories (ENP-DROM 2021). Multivariate poisson regressions were employed to study the following determinants: age, educational level, monthly household income, socio-professional situation, birth country, parity, health professional who monitored pregnancy, influenza vaccination during pregnancy, region of residence, prenatal care consultations, having health insurance, having a partner, and having a chronic pathology. Results were weighted.

Results

The study sample comprised 7999 women. Estimated pertussis VC at two months postpartum was 66.8 % (95 %CI [65.5–68.0]).

VC was significantly lower in i) unemployed women (vs. executives/managers, intermediate and higher intellectual professionals), ii) those on low income (vs. high), and iii) those with two or more children (vs. primiparous). It was significantly higher in i) women born in France, ii) those vaccinated against influenza during pregnancy, iii) those who received pre-natal care from a private midwife, and iv) those with more prenatal consultations.

The proportion of women vaccinated against pertussis in the two-month postpartum period (33.4 % [31.7–35.9]) was significantly lower in i) women on low incomes, ii) unemployed women, iii) women with health insurance, and iv) multiparous women. It was significantly higher in those vaccinated against influenza during pregnancy.

Discussion - Conclusion

Pertussis VC in women at two months postpartum in 2021 was insufficient and was marked by social and territorial inequalities in health. Vaccination for pregnant women has been recommended in France since 2022. A study monitoring the impact of this new recommendation is essential.

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来源期刊

Vaccine 医学-免疫学

CiteScore

8.70

自引率

5.50%

发文量

992

审稿时长

131 days

期刊介绍： Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.