通过混合[18F]FDG-PET检测晚期头颈部鳞状细胞癌的复发情况

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2024-11-08 DOI:10.1002/hed.27997

Oliver P Sutter, Alexander Maurer, Thomas M Stadler, Martin Lanzer, Martin W Huellner, Martina A Broglie

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引用次数: 0

摘要

背景：在晚期头颈部鳞状细胞癌的临床治疗中，混合[18F]FDG-PET成像的应用已得到广泛认可。然而，关于混合 PET 扫描纳入随访方案的最佳频率，尤其是在首次治疗后扫描结果为阴性的情况下，一直存在争议：我们进行了一项为期 10 年的单中心回顾性研究，涉及所有接受混合 PET 扫描的晚期头颈癌随访患者。共纳入 285 例患者：结果：在199名3个月混合正电子发射计算机断层扫描结果为阴性的患者中，有15%的患者在后续随访中复发。值得注意的是，90%的复发是通过混合 PET 检测到的：结论：3 个月混合 PET 阴性的患者中有 15% 复发。鉴于大多数复发是通过混合 PET 扫描发现的，因此在随访期间定期进行重复扫描是有说服力的。

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Recurrence Detection by Hybrid [¹⁸F]FDG-PET in Advanced Head and Neck Squamous Cell Carcinoma.

Background: In the clinical management of advanced stage head and neck squamous cell carcinoma, the use of hybrid [¹⁸F]FDG-PET imaging is well established. However, there is ongoing debate regarding the optimal frequency of hybrid PET scans to be included in follow-up protocols, particularly if the initial post-therapeutic scan is negative.

Methods: We conducted a single-center 10-year retrospective study involving all patients who underwent hybrid PET scans for the follow-up of advanced stage head and neck cancer. A total of 285 patients were included.

Results: Out of 199 patients with a negative 3-month hybrid PET, 15% subsequently developed a recurrence during further follow-up. Notably, 90% of these recurrences were detected by hybrid PET.

Conclusion: Fifteen percent of patients with a negative 3-month hybrid PET experienced a recurrence. Given that the majority of recurrences were detected by hybrid PET scans, there is a compelling argument for incorporating regular repetitive scans during follow-up.

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.