慢性阻塞性肺疾病恶化患者入院前呼吸科专家会诊与改善管理和疗效有关。

IF 2.7 3区 医学 Q2 RESPIRATORY SYSTEM
Ariel Melloul, Ophir Freund, Boaz Tiran, Tal Moshe Perluk, Netanel Golan, Eyal Kleinhendler, Evgeni Gershman, Avraham Unterman, Avishay Elis, Amir Bar-Shai
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引用次数: 0

摘要

目的:慢性阻塞性肺病(ECOPD)加重对疾病进展和死亡率有重大影响。在病情加重时就近就诊呼吸专科医师(RS)可能有助于及时治疗并改善预后。我们旨在评估入院前 30 天到呼吸专科就诊与病情加重结果之间的关系:这项前瞻性研究纳入了 2017 年至 2019 年期间在 13 个医疗中心因 ECOPD 住院的受试者。采用倾向得分匹配法对入院前、院内和 30 天的预后进行评估,并对 30 天内进行过 RS 访问的患者和未进行过 RS 访问的患者进行比较。根据进行 RS 访问的原因(紧急访问与定期随访)进行了分组分析:结果:共纳入 344 名受试者,其中 105 人(31%)在入院前接受过 RS 检查(RS 组)。配对前,RS 组中严重慢性阻塞性肺病的指标较高,而配对后则无差异。RS 就诊与院前开始使用短效支气管扩张剂(50% 对 36%)、抗生素(30% 对 17%)和全身类固醇(38% 对 22%)有关。RS 组从首次出现症状到到达医院的时间更长(中位数为 5 天 vs 3 天,p < 0.01),住院时间更短(中位数为 4 天 vs 5 天,p = 0.04)。两组患者的住院和 30 天疗效相似。然而,非紧急的院前 RS 访问与住院和 30 天预后的改善有关:常规 RS 访问可为 ECOPD 提供正确的早期治疗,并有可能改善预后。这些研究结果突出表明,需要有可用的专家和更高的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Respiratory Specialist Visits Before Admissions with COPD Exacerbation are Linked to Improved Management and Outcomes.

Purpose: Exacerbations of COPD (ECOPD) significantly impact disease progression and mortality. Visiting a respiratory specialist (RS) in proximity to the exacerbation may lead to prompt treatment and improved outcomes. We aimed to evaluate the association between an RS visit 30-days before admission and exacerbation outcomes.

Patients and methods: The prospective study included subjects that were hospitalized with ECOPD between 2017 and 2019 in 13 medical centers. Pre-admission, in-hospital, and 30-day outcomes were assessed and compared between patients with and without a 30-day RS visit, using propensity score matching. A sub-group analysis was performed based on the reason for the RS visit (emergent vs regular follow-up).

Results: Three hundred and forty-four subjects were included, and 105 (31%) had pre-admission RS visit (RS group). Before matching, indicators of severe COPD were prevalent in the RS group, while after matching there were no differences. RS visits were associated with pre-hospital initiation of short acting bronchodilators (50% vs 36%), antibiotics (30% vs 17%), and systemic steroids (38% vs 22%). The RS group had longer duration between first symptoms to hospital arrival (median 5 vs 3 days, p < 0.01) and shorter hospital length-of-stay (median 4 vs 5 days, p = 0.04). In-hospital and 30-days outcomes were similar between the groups. However, a non-emergent pre-hospital RS visit was associated with improved in-hospital and 30-day outcomes.

Conclusion: Routine RS visits could lead to correct and early treatment for ECOPD with a potential for improved outcomes. These findings highlight the need for available specialists and higher awareness.

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来源期刊
CiteScore
4.80
自引率
10.70%
发文量
372
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed journal of therapeutics and pharmacology focusing on concise rapid reporting of clinical studies and reviews in COPD. Special focus will be given to the pathophysiological processes underlying the disease, intervention programs, patient focused education, and self management protocols. This journal is directed at specialists and healthcare professionals
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