Angela Xia, Vishal Mehta, Victoria Wei, Alexander Andreev, Robert Regenhardt
{"title":"伪装成高级别胶质瘤的 CAA-ri：病例报告。","authors":"Angela Xia, Vishal Mehta, Victoria Wei, Alexander Andreev, Robert Regenhardt","doi":"10.1177/19418744241296198","DOIUrl":null,"url":null,"abstract":"<p><p>This case describes a 76-year-old male with initial clinical concern for a high-grade glioma, who was ultimately diagnosed with cerebral amyloid angiopathy-related inflammation The patient's presentation included a tonic-clonic seizure followed by aphasia and right-sided hemiparesis. Magnetic resonance brain imaging demonstrated a large left frontal lesion with parenchymal contrast enhancement. Magnetic resonance spectroscopy indicated elevated choline to creatine and choline to N-acetyl aspartate ratios, further suggestive of high-grade glioma. However, subsequent biopsy findings revealed perivascular amyloid deposits, confirming the diagnosis of CAA-ri. To our knowledge, this is the first case in literature to report elevated choline to creatine and choline to N-acetyl aspartate ratios in cerebral amyloid angiopathy-related inflammation.</p>","PeriodicalId":46355,"journal":{"name":"Neurohospitalist","volume":" ","pages":"19418744241296198"},"PeriodicalIF":0.9000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559454/pdf/","citationCount":"0","resultStr":"{\"title\":\"CAA-ri Masquerading as a High-Grade Glioma: A Case Report.\",\"authors\":\"Angela Xia, Vishal Mehta, Victoria Wei, Alexander Andreev, Robert Regenhardt\",\"doi\":\"10.1177/19418744241296198\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This case describes a 76-year-old male with initial clinical concern for a high-grade glioma, who was ultimately diagnosed with cerebral amyloid angiopathy-related inflammation The patient's presentation included a tonic-clonic seizure followed by aphasia and right-sided hemiparesis. Magnetic resonance brain imaging demonstrated a large left frontal lesion with parenchymal contrast enhancement. Magnetic resonance spectroscopy indicated elevated choline to creatine and choline to N-acetyl aspartate ratios, further suggestive of high-grade glioma. However, subsequent biopsy findings revealed perivascular amyloid deposits, confirming the diagnosis of CAA-ri. To our knowledge, this is the first case in literature to report elevated choline to creatine and choline to N-acetyl aspartate ratios in cerebral amyloid angiopathy-related inflammation.</p>\",\"PeriodicalId\":46355,\"journal\":{\"name\":\"Neurohospitalist\",\"volume\":\" \",\"pages\":\"19418744241296198\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559454/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurohospitalist\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/19418744241296198\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurohospitalist","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/19418744241296198","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
CAA-ri Masquerading as a High-Grade Glioma: A Case Report.
This case describes a 76-year-old male with initial clinical concern for a high-grade glioma, who was ultimately diagnosed with cerebral amyloid angiopathy-related inflammation The patient's presentation included a tonic-clonic seizure followed by aphasia and right-sided hemiparesis. Magnetic resonance brain imaging demonstrated a large left frontal lesion with parenchymal contrast enhancement. Magnetic resonance spectroscopy indicated elevated choline to creatine and choline to N-acetyl aspartate ratios, further suggestive of high-grade glioma. However, subsequent biopsy findings revealed perivascular amyloid deposits, confirming the diagnosis of CAA-ri. To our knowledge, this is the first case in literature to report elevated choline to creatine and choline to N-acetyl aspartate ratios in cerebral amyloid angiopathy-related inflammation.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
