患有腹膜子宫内膜异位症的不孕患者体内抗核（抗Sm）抗体增加。

IF 1.8 Q3 OBSTETRICS & GYNECOLOGY

Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-11-14 DOI:10.5935/1518-0557.20240070

Renata Fogaça Borges, Vanessa Krebs Genro, Carlos Augusto Bastos de Souza, Tatiana Ferreira Michelon, Isabel Meneghetti Coimbra, João Sabino Lahorgue da Cunha-Filho

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引用次数: 0

摘要

研究目的本研究旨在评估子宫内膜异位症不孕患者体内针对可提取核抗原（ENA：RNP、ScL-70、SS-B、SS-A和Sm）的五种抗体的强度：方法：我们对患有轻度/中度子宫内膜异位症的不孕妇女（43 人）和已育妇女（46 人）进行了调查：结果：抗RNP抗体和抗SS-A抗体的免疫反应强度相似。结果：抗RNP抗体和抗SS-A抗体的免疫反应强度相似，但抗Sm抗体的免疫反应强度在子宫内膜异位症组较高：结论：轻度/中度子宫内膜异位症患者的抗Sm自身抗体水平较高。

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Increased antinuclear (anti-Sm) antibodies in infertile patients with peritoneal endometriosis.

Objective: The aim of this study is to evaluate the intensity of five antibodies against extractable nuclear antigens (ENA: RNP, ScL-70, SS-B, SS-A, and Sm) in infertile patients with endometriosis.

Methods: We investigated infertile women with minimal/mild endometriosis (n=43) and fertile women (n=46).

Results: The intensity of immunoreactions was also similar for anti-RNP and anti-SS-A antibodies. However, the intensity of immunoreactivity for anti-Sm antibodies was higher in the endometriosis group.

Conclusions: Patients with minimal/mild endometriosis have higher levels of anti-Sm autoantibodies.

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来源期刊

Jornal Brasileiro de Reproducao Assistida OBSTETRICS & GYNECOLOGY-

CiteScore

3.30

自引率

6.70%

发文量