Evelin Tiralongo, Vanessa Vigar, Keith Potent, Robert S Ware
{"title":"多草药能增强健康老年人的认知能力吗？一项探索性开放标签研究","authors":"Evelin Tiralongo, Vanessa Vigar, Keith Potent, Robert S Ware","doi":"10.1089/jicm.2023.0620","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Objective:</i></b> This 12-week open-label study evaluated a multi-herbal tablet containing <i>Reynoutria japonica</i>, <i>Vitis vinifera</i>, <i>Silybum marianum</i>, <i>Ginkgo biloba</i>, and <i>Panax ginseng</i>, for potential improvement of cognitive function in 25 healthy older adults (50-75 years). <b><i>Methods:</i></b> The primary outcome, cognition, was assessed using the Cambridge Neuropsychological Test Automated Battery. <b><i>Results:</i></b> Significant improvement in working memory was observed. Errors in the Paired Associate Learning (PAL) task and spatial working memory reduced by -7.9 (95%CI: -12.3, -3.5) and -3.3 (95%CI: -6.3, -0.3) respectively, while PAL memory score increased by 2.0 (95%CI: 0.9, 3.1). <i><b>Conclusion:</b></i> These preliminary results suggest memory improvement, but further rigorous testing is needed.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"209-213"},"PeriodicalIF":1.3000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Does a Polyherbal Medicine Enhance Cognition in Healthy Older Adults? An Exploratory Open-Label Study.\",\"authors\":\"Evelin Tiralongo, Vanessa Vigar, Keith Potent, Robert S Ware\",\"doi\":\"10.1089/jicm.2023.0620\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Objective:</i></b> This 12-week open-label study evaluated a multi-herbal tablet containing <i>Reynoutria japonica</i>, <i>Vitis vinifera</i>, <i>Silybum marianum</i>, <i>Ginkgo biloba</i>, and <i>Panax ginseng</i>, for potential improvement of cognitive function in 25 healthy older adults (50-75 years). <b><i>Methods:</i></b> The primary outcome, cognition, was assessed using the Cambridge Neuropsychological Test Automated Battery. <b><i>Results:</i></b> Significant improvement in working memory was observed. Errors in the Paired Associate Learning (PAL) task and spatial working memory reduced by -7.9 (95%CI: -12.3, -3.5) and -3.3 (95%CI: -6.3, -0.3) respectively, while PAL memory score increased by 2.0 (95%CI: 0.9, 3.1). <i><b>Conclusion:</b></i> These preliminary results suggest memory improvement, but further rigorous testing is needed.</p>\",\"PeriodicalId\":29734,\"journal\":{\"name\":\"Journal of Integrative and Complementary Medicine\",\"volume\":\" \",\"pages\":\"209-213\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Integrative and Complementary Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1089/jicm.2023.0620\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Integrative and Complementary Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/jicm.2023.0620","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
研究目的这项为期 12 周的开放标签研究评估了一种含有雷诺丽珠、葡萄籽、水飞蓟、银杏叶和三七的多草药片剂对 25 名健康老年人（50-75 岁）认知功能的潜在改善作用。研究方法使用剑桥神经心理测试自动化电池对认知能力这一主要结果进行评估。结果观察到工作记忆有明显改善。配对联想学习（PAL）任务和空间工作记忆的错误率分别降低了-7.9（95%CI：-12.3，-3.5）和-3.3（95%CI：-6.3，-0.3），而 PAL 记忆得分则提高了 2.0（95%CI：0.9，3.1）。结论这些初步结果表明记忆力有所改善，但还需要进一步的严格测试。
Does a Polyherbal Medicine Enhance Cognition in Healthy Older Adults? An Exploratory Open-Label Study.
Objective: This 12-week open-label study evaluated a multi-herbal tablet containing Reynoutria japonica, Vitis vinifera, Silybum marianum, Ginkgo biloba, and Panax ginseng, for potential improvement of cognitive function in 25 healthy older adults (50-75 years). Methods: The primary outcome, cognition, was assessed using the Cambridge Neuropsychological Test Automated Battery. Results: Significant improvement in working memory was observed. Errors in the Paired Associate Learning (PAL) task and spatial working memory reduced by -7.9 (95%CI: -12.3, -3.5) and -3.3 (95%CI: -6.3, -0.3) respectively, while PAL memory score increased by 2.0 (95%CI: 0.9, 3.1). Conclusion: These preliminary results suggest memory improvement, but further rigorous testing is needed.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
