[食道小细胞神经内分泌癌:病例报告和文献综述]。

Q4 Medicine
Johana Lipiejko, Ignacio Moratorio, Adrián Canavesi
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引用次数: 0

摘要

食道癌是一种预后不良的恶性肿瘤。食管神经内分泌肿瘤非常罕见,比例不到 2%。临床表现为永久性、进行性吞咽困难和全身影响时,通常属于局部晚期肿瘤,预后较差。我们介绍了一例因持续性、进行性吞咽困难就医的 45 岁男性病例,他被诊断为食道神经内分泌癌。诊断是通过内窥镜检查得出的,内窥镜检查发现了一个占食管周径四分之三的广泛、植物性和狭窄性病变。组织学确诊为分化不良的小细胞恶性肿瘤,嗜铬粒蛋白 A 和突触素免疫组化阳性。鉴于诊断结果为食道小细胞神经内分泌癌,并伴有局部扩展,IV 期,建议采用化疗、放疗和经皮内镜胃切除术进行姑息治疗,患者的生存期仅为 6 个月。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Small cell neuroendocrine carcinoma of the oesophagus: case report and literature review].

Oesophageal cancer corresponds to a malignant neoplasm with a poor prognosis. Neuroendocrine tumors of the esophagus are very rare, accounting for less than 2%. When clinically manifested by permanent, progressive dysphagia and general impact, they usually correspond to locally advanced tumors with a poor prognosis. We present the case of a 45-year-old man who attended medical attention for persistent and progressive dysphagia, who was diagnosed with neuroendocrine carcinoma of the oesophagus. The diagnosis was reached through endoscopy, revealing an extensive, vegetative and stenosing lesion occupying three-quarters of the oesophageal circumference. Histology confirmed the diagnosis of poorly differentiated small cell malignancy with positive immunohistochemistry for chromogranin A and synaptophysin. In light of the diagnosis of small cell neuroendocrine carcinoma of the oesophagus with locaregional extension, stage IV, palliative treatment with chemotherapy, radiotherapy and percutaneous endoscopic gastronomy was proposed, with a survival of only 6 months.

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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
49
期刊介绍: La REVISTA DE GASTROENTEROLOGíA DEL PERÚ, es la publicación oficial de la Sociedad de Gastroenterología del Perú que publica artículos originales, artículos de revisión, reporte de casos, cartas e información general de la especialidad; dirigido a los profesionales de la salud con especial interés en la gastroenterología. La Revista de Gastroenterología del Perú es una publicación de periodicidad trimestral y tiene como objetivo la publicación de artículos científicos inéditos en el campo de la gastroenterología, proporcionando información actualizada y relevante de la especialidad y áreas afines. La Revista de Gastroenterología del Perú publica artículos en dos idiomas, español e inglés, a texto completo en la versión impresa yelectrónica. Los artículos científicos son sometidos a revisores o árbitros nacionales e internacionales, especialistas que opinan bajo la modalidad de doble ciego y de manera anónima sobre la calidad y validez de los mismos. El número de revisores depende del tipo de artículo, dos revisores como mínimo para artículos originales y uno como mínimo para otros tipos de artículos.
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