基于微气泡造影剂的二次谐波聚焦超声装置研究。

IF 3.8 2区物理与天体物理 Q1 ACOUSTICS

Ultrasonics Pub Date : 2024-11-09 DOI:10.1016/j.ultras.2024.107514

Qinglei Zeng , Yuetongxu Li , Zhaoyu Deng , Gutian Zhang , Chengwei Zhang , Haifeng Huang , Xiaozhou Liu

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引用次数: 0

摘要

无创、准确的诊断和治疗越来越受到医学研究的关注。超声造影剂的非线性响应机制及其医学应用已成为超声成像研究的主要课题。本文报告了一种基于微气泡造影剂的二次谐波聚焦超声装置，旨在解决二次谐波强度较弱的相关问题。在特定形状的树脂板中心嵌入了周期性的圆孔阵列，并使用薄树脂带将造影剂封装在圆孔中。该装置的功能机制得到了理论解释和实验验证。与不使用该装置的传统系统相比，该装置能以更高的超声横向分辨率和信噪比进行二次谐波超声成像。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Research on the second-harmonic focused ultrasonic device based on micro-bubble contrast agents

Non-invasive, accurate diagnosis and treatment have increasingly gained attention in medical research. The nonlinear response mechanism of ultrasound contrast agents and their medical application have become major topics in ultrasound imaging studies. This paper reports on a second-harmonic focused ultrasonic device based on micro-bubble contrast agents, which is designed to solve the problems associated with a weak second-harmonic intensity. A periodic array of circular holes is embedded in the center of a specifically shaped resin plate, and contrast agents are encapsulated in the circular holes using thin resin tape. The functional mechanism is theoretically explained and experimentally verified. This device enables second-harmonic ultrasound imaging with a higher ultrasonic lateral resolution and signal-to-noise ratio than the conventional system without the device.

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来源期刊

Ultrasonics 医学-核医学

CiteScore

7.60

自引率

19.00%

发文量

186

审稿时长

3.9 months

期刊介绍： Ultrasonics is the only internationally established journal which covers the entire field of ultrasound research and technology and all its many applications. Ultrasonics contains a variety of sections to keep readers fully informed and up-to-date on the whole spectrum of research and development throughout the world. Ultrasonics publishes papers of exceptional quality and of relevance to both academia and industry. Manuscripts in which ultrasonics is a central issue and not simply an incidental tool or minor issue, are welcomed. As well as top quality original research papers and review articles by world renowned experts, Ultrasonics also regularly features short communications, a calendar of forthcoming events and special issues dedicated to topical subjects.