在温暖天气下进行 7 英里长跑比赛后,白细胞介素 (IL)-6、8 和 10 的变化及其与核心体温升高的关系。

IF 1.9 3区 医学 Q2 SPORT SCIENCES
Yasuki Sekiguchi, Yuri Hosokawa, Ekow Dadzie, Virgilio Lopez, Joseph J Bivona, Staci N Thornton, John F Jardine, Douglas J Casa, Elaine C Lee
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IL-6, IL-8, and IL-10 significantly increased at post-race (IL-6, 48.0 ± 22.3 pg⋅ml<sup>-1</sup>; IL-8, 63.8 ± 23.9 pg⋅ml<sup>-1</sup>; IL-10, 29.2 ± 20.0 pg⋅ml<sup>-1</sup>) compared to pre-race (IL-6, 28.4 ± 13.6 pg⋅ml<sup>-1</sup>; IL-8, 53.2 ± 19.4 pg⋅ml<sup>-1</sup>; IL-10, 18.6 ± 11.9 pg⋅ml<sup>-1</sup>, <i>p</i> < 0.001). A greater increase in core temperature pre- to post-race was predicted by the faster finish time, a greater increase in IL-6, and greater body mass loss during the race (r<sup>2</sup> = 0.298, <i>p</i> < 0.001). Small associations were found between IL-8 and core temperature at post-race (<i>r</i> = 0.255, <i>p</i> = 0.025). In conclusion, cytokines concentrations and core temperature increased following the race. 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引用次数: 0

摘要

本研究的目的是:1)调查路跑后细胞因子是否增加;2)研究细胞因子与高热之间的关系。有 77 名休闲跑步者参加了这项研究,他们在高温下参加了 7 英里的比赛(环境温度为 25.0-26.7°C;相对湿度为 56.7-79.0 ± 5.0%)。赛前和赛后都进行了抽血,以测量循环炎症细胞因子。在整个比赛过程中,使用可摄取式温度计测量核心温度。赛后的核心温度(39.5 ± 0.7°C)明显高于赛前(36.9 ± 0.4°C,p -1;IL-8,63.8 ± 23.9 pg-ml-1;IL-10,29.2 ± 20.0 pg-ml-1)。0 pg-ml-1)相比(IL-6,28.4 ± 13.6 pg-ml-1;IL-8,53.2 ± 19.4 pg-ml-1;IL-10,18.6 ± 11.9 pg-ml-1,p 2 = 0.298,p r = 0.255,p = 0.025)。总之,赛后细胞因子浓度和核心温度升高。此外,赛后高热与 IL-6 增加、更快的完赛时间和更高的体重损失有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Change in interleukin (IL)-6, 8, and 10 and its association with an increase in core temperature following a 7-mile running race in the warm weather.

The purposes of this study were 1) to investigate if cytokines were increased following a running road-race, and 2) to examine associations between cytokines and hyperthermia. Seventy-seven recreational runners participated in this study which occurred at the 7-mile race in the heat (ambient temperature, 25.0-26.7°C; %RH, 56.7-79.0 ± 5.0%). Before and following the race, blood draws were performed to measure circulating inflammatory cytokines. Core temperature was measured using an ingestible thermistor throughout the race. Core temperature was significantly higher at post-race (39.5 ± 0.7°C) than pre-race (36.9 ± 0.4°C, p < 0.001). IL-6, IL-8, and IL-10 significantly increased at post-race (IL-6, 48.0 ± 22.3 pg⋅ml-1; IL-8, 63.8 ± 23.9 pg⋅ml-1; IL-10, 29.2 ± 20.0 pg⋅ml-1) compared to pre-race (IL-6, 28.4 ± 13.6 pg⋅ml-1; IL-8, 53.2 ± 19.4 pg⋅ml-1; IL-10, 18.6 ± 11.9 pg⋅ml-1, p < 0.001). A greater increase in core temperature pre- to post-race was predicted by the faster finish time, a greater increase in IL-6, and greater body mass loss during the race (r2 = 0.298, p < 0.001). Small associations were found between IL-8 and core temperature at post-race (r = 0.255, p = 0.025). In conclusion, cytokines concentrations and core temperature increased following the race. Moreover, post-race hyperthermia is associated with increased IL-6, faster finish times, and higher body mass losses.

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来源期刊
Research in Sports Medicine
Research in Sports Medicine SPORT SCIENCES-
CiteScore
6.40
自引率
0.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Research in Sports Medicine is a broad journal that aims to bridge the gap between all professionals in the fields of sports medicine. The journal serves an international audience and is of interest to professionals worldwide. The journal covers major aspects of sports medicine and sports science - prevention, management, and rehabilitation of sports, exercise and physical activity related injuries. The journal publishes original research utilizing a wide range of techniques and approaches, reviews, commentaries and short communications.
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