Shunhe Lin, Xi Xie, Yishan Chen, Zhenna Wang, Jinna Zhang, Chaobin Liu, Guan Lin, Yi Wang, Yuyan Guo
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引用次数: 0
摘要
背景：子宫内膜异位症（EMS）和慢性子宫内膜炎（CE）经常同时存在。本研究旨在探讨CE对EMS患者生殖结局的影响：我们在 2018 年 1 月至 2020 年 12 月期间招募了 685 名子宫内膜异位症相关不孕症患者。患者被分为CE组（318人）和非CE组（367人）。从 CE 组和非 CE 组分别选出 123 名临床妊娠妇女和 369 名临床妊娠妇女进行详细比较。妊娠和分娩数据均通过医院记录和电话访谈进行了细致收集：结果：46.42%的 EMS 患者被诊断为 CE。子宫内膜异位症生育指数（EFI）为 7-10 分的患者妊娠率较高。患有 CE 的 EMS 患者发生前置胎盘（13.01%）、妊娠高血压（5.69%）和剖宫产（59.34%）的风险增加：EMS患者中普遍存在的CE与妊娠并发症风险增加有关，包括前置胎盘、妊娠高血压和剖宫产。虽然宫腔镜和腹腔镜联合检查可提高妊娠率，但需要对这些并发症进行谨慎处理。
How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study.
Background: Endometriosis (EMS) and chronic endometritis (CE) frequently coexist. This study aimed to examine the impact of CE on reproductive outcomes in patients with EMS.
Methods: We enrolled 685 patients with endometriosis-associated infertility from January 2018 to December 2020. The patients were divided into CE (318) and non-CE (367) groups. A subset of 123 clinically pregnant women from the CE group and 369 from the non-CE group was selected for detailed comparison. Pregnancy and delivery data were meticulously collected from hospital records and through telephone interviews.
Results: CE was diagnosed in 46.42% of EMS patients. Higher pregnancy rates were observed in patients with Endometriosis Fertility Index (EFI) scores of 7-10. EMS patients with CE had increased risks of placenta previa (13.01%), gestational hypertension (5.69%), and cesarean sections (59.34%).
Conclusions: CE, which is prevalent among EMS patients, is linked to increased risks of pregnancy complications, including placenta previa, gestational hypertension, and cesarean delivery. Although combined hysteroscopy and laparoscopy improve pregnancy rates, they demand careful management of these complications.
期刊介绍：
Reproductive Health focuses on all aspects of human reproduction. The journal includes sections dedicated to adolescent health, female fertility and midwifery and all content is open access.
Reproductive health is defined as a state of physical, mental, and social well-being in all matters relating to the reproductive system, at all stages of life. Good reproductive health implies that people are able to have a satisfying and safe sex life, the capability to reproduce and the freedom to decide if, when, and how often to do so. Men and women should be informed about and have access to safe, effective, affordable, and acceptable methods of family planning of their choice, and the right to appropriate health-care services that enable women to safely go through pregnancy and childbirth.
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