Kelly Young, Ian Loveless, Wan-Ting K Su, Jesse Veenstra, Congcong Yin, Peter Dimitrion, Rachel Krevh, Li Zhou, Ruicong She, Mingming Pan, Albert M Levin, Albert Young, Eglal Samir, Andrea Dai, James Ge, Richard H Huggins, Cristina de Guzman Strong, Henry W Lim, David M Ozog, Iltefat Hamzavi, Indra Adrianto, Qing-Sheng Mi
{"title":"多样化的化脓性扁桃体炎队列：对美国大型医疗保健系统数据库中 1995-2022 年间的 13130 名患者进行的回顾性横断面研究。","authors":"Kelly Young, Ian Loveless, Wan-Ting K Su, Jesse Veenstra, Congcong Yin, Peter Dimitrion, Rachel Krevh, Li Zhou, Ruicong She, Mingming Pan, Albert M Levin, Albert Young, Eglal Samir, Andrea Dai, James Ge, Richard H Huggins, Cristina de Guzman Strong, Henry W Lim, David M Ozog, Iltefat Hamzavi, Indra Adrianto, Qing-Sheng Mi","doi":"10.1016/j.jaad.2024.10.073","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Most epidemiological studies of hidradenitis suppurativa (HS) have described homogeneous patient populations.</p><p><strong>Objective: </strong>To characterize demographics, modifiable health behaviors, and comorbidities of HS patients within a diverse cohort.</p><p><strong>Methods: </strong>A retrospective cross-sectional study of 13,130 HS patients within a healthcare system was conducted.</p><p><strong>Results: </strong>A female sex bias of ∼3:1 in all racial/ethnic subgroups was observed. Black/African American (AA) patients had a lower age at HS diagnosis than White patients (37.1 years vs 39.4 years, P<0.001). A higher proportion of Black/AA females than White females with HS had BMI in the obese range (69.9% vs 56.5%; P=0.03). In contrast, fewer Black/African American males with HS had a BMI in the obese range compared to White males (51.4% vs. 61.0%; P<0.001). More Black/AA patients than White patients with HS had congestive heart failure (OR=2.10, CI=1.19-3.78; P<0.05), chronic pulmonary disease (OR=1.34; CI=1.02-1.78; P<0.05), diabetes with chronic complication (OR=1.73; CI=1.16-2.60; P<0.05), renal disease (OR=2.66; CI=1.67-4.34; P<0.05), and Charlson Comorbidity Index score ≥4 (OR=1.67; CI=1.09-2.58; P<0.05). Furthermore, male patients were more likely than female patients to have renal disease (OR=2.62; CI 1.66-4.14; P<0.05).</p><p><strong>Limitations: </strong>A single-center study.</p><p><strong>Conclusion: </strong>Subgroups of HS patients had significant differences in demographics, risk factors, and comorbid conditions.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8000,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A diverse hidradenitis suppurativa cohort: a retrospective cross-sectional study of 13,130 patients from a large US healthcare system database from 1995-2022.\",\"authors\":\"Kelly Young, Ian Loveless, Wan-Ting K Su, Jesse Veenstra, Congcong Yin, Peter Dimitrion, Rachel Krevh, Li Zhou, Ruicong She, Mingming Pan, Albert M Levin, Albert Young, Eglal Samir, Andrea Dai, James Ge, Richard H Huggins, Cristina de Guzman Strong, Henry W Lim, David M Ozog, Iltefat Hamzavi, Indra Adrianto, Qing-Sheng Mi\",\"doi\":\"10.1016/j.jaad.2024.10.073\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Most epidemiological studies of hidradenitis suppurativa (HS) have described homogeneous patient populations.</p><p><strong>Objective: </strong>To characterize demographics, modifiable health behaviors, and comorbidities of HS patients within a diverse cohort.</p><p><strong>Methods: </strong>A retrospective cross-sectional study of 13,130 HS patients within a healthcare system was conducted.</p><p><strong>Results: </strong>A female sex bias of ∼3:1 in all racial/ethnic subgroups was observed. Black/African American (AA) patients had a lower age at HS diagnosis than White patients (37.1 years vs 39.4 years, P<0.001). A higher proportion of Black/AA females than White females with HS had BMI in the obese range (69.9% vs 56.5%; P=0.03). In contrast, fewer Black/African American males with HS had a BMI in the obese range compared to White males (51.4% vs. 61.0%; P<0.001). More Black/AA patients than White patients with HS had congestive heart failure (OR=2.10, CI=1.19-3.78; P<0.05), chronic pulmonary disease (OR=1.34; CI=1.02-1.78; P<0.05), diabetes with chronic complication (OR=1.73; CI=1.16-2.60; P<0.05), renal disease (OR=2.66; CI=1.67-4.34; P<0.05), and Charlson Comorbidity Index score ≥4 (OR=1.67; CI=1.09-2.58; P<0.05). Furthermore, male patients were more likely than female patients to have renal disease (OR=2.62; CI 1.66-4.14; P<0.05).</p><p><strong>Limitations: </strong>A single-center study.</p><p><strong>Conclusion: </strong>Subgroups of HS patients had significant differences in demographics, risk factors, and comorbid conditions.</p>\",\"PeriodicalId\":17198,\"journal\":{\"name\":\"Journal of the American Academy of Dermatology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":12.8000,\"publicationDate\":\"2024-11-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the American Academy of Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jaad.2024.10.073\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Academy of Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jaad.2024.10.073","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
A diverse hidradenitis suppurativa cohort: a retrospective cross-sectional study of 13,130 patients from a large US healthcare system database from 1995-2022.
Background: Most epidemiological studies of hidradenitis suppurativa (HS) have described homogeneous patient populations.
Objective: To characterize demographics, modifiable health behaviors, and comorbidities of HS patients within a diverse cohort.
Methods: A retrospective cross-sectional study of 13,130 HS patients within a healthcare system was conducted.
Results: A female sex bias of ∼3:1 in all racial/ethnic subgroups was observed. Black/African American (AA) patients had a lower age at HS diagnosis than White patients (37.1 years vs 39.4 years, P<0.001). A higher proportion of Black/AA females than White females with HS had BMI in the obese range (69.9% vs 56.5%; P=0.03). In contrast, fewer Black/African American males with HS had a BMI in the obese range compared to White males (51.4% vs. 61.0%; P<0.001). More Black/AA patients than White patients with HS had congestive heart failure (OR=2.10, CI=1.19-3.78; P<0.05), chronic pulmonary disease (OR=1.34; CI=1.02-1.78; P<0.05), diabetes with chronic complication (OR=1.73; CI=1.16-2.60; P<0.05), renal disease (OR=2.66; CI=1.67-4.34; P<0.05), and Charlson Comorbidity Index score ≥4 (OR=1.67; CI=1.09-2.58; P<0.05). Furthermore, male patients were more likely than female patients to have renal disease (OR=2.62; CI 1.66-4.14; P<0.05).
Limitations: A single-center study.
Conclusion: Subgroups of HS patients had significant differences in demographics, risk factors, and comorbid conditions.
期刊介绍：
The Journal of the American Academy of Dermatology (JAAD) is the official scientific publication of the American Academy of Dermatology (AAD). Its primary goal is to cater to the educational requirements of the dermatology community. Being the top journal in the field, JAAD publishes original articles that have undergone peer review. These articles primarily focus on clinical, investigative, and population-based studies related to dermatology. Another key area of emphasis is research on healthcare delivery and quality of care. JAAD also highlights high-quality, cost-effective, and innovative treatments within the field. In addition to this, the journal covers new diagnostic techniques and various other topics relevant to the prevention, diagnosis, and treatment of skin, hair, and nail disorders.
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