Application Value of Two-Dimensional Ultrasound Combined With Three-Dimensional Power Doppler in the Prediction of Macrosomia in Early Pregnancy.

Objective: To investigate the value of two-dimensional (2D) ultrasound combined with three-dimensional power Doppler (3D-PD) in the prediction of macrosomia in early pregnancy.

Methods: A total of 171 singleton pregnant women who underwent prenatal ultrasound examination at 11⁺⁰-13⁺⁶ weeks of gestation in the First Affiliated Hospital of Shihezi University from October 2021 to October 2022 were selected as the research subjects. They were followed up until delivery. Their general data and Doppler ultrasound parameters were recorded and analyzed. The differences in ultrasound data between the two groups were compared, and the receiver operating characteristic (ROC) curve was drawn to evaluate the parameters.

Results: Compared with the normal group, the macrosomia group had significantly higher biparietal diameter, placental volume, and placental microvascular index (p < 0.05).

Conclusions: Increased placental vascular perfusion occurs in macrosomia during early pregnancy. The vascularization-flow index (VFI) had a high predictive value for macrosomia (AUC = 0.826), and 2D ultrasound combined with 3D-PD had the best predictive efficiency for macrosomia in early pregnancy (AUC = 0.926). Future studies should also consider combining maternal and fetal factors to predict macrosomia, to reduce the occurrence of adverse pregnancy outcomes.