注意缺陷多动障碍(ADHD)合并囤积症成年患者复杂的临床和认知表型。

IF 2.9 4区 医学 Q2 PSYCHIATRY
Giacomo Grassi, Corinna Moradei, Chiara Cecchelli, Michael van Ameringen
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引用次数: 0

摘要

研究目的多项研究一致表明,注意力缺陷多动障碍(ADHD)患者合并囤积症(HD)的比例很高。本研究旨在通过自我报告测量方法,比较有囤积症合并症和无囤积症合并症的成年注意力缺陷多动障碍(ADHD)患者与健康对照组样本的临床和认知特征:本研究连续招募了57名初诊为多动症并发囤积症(ADHD+HD)的成年门诊患者、57名匹配的无囤积症并发症(ADHD-HD)的多动症患者,以及由47名健康对照组(HC)组成的对照组。所有受试者都接受了全面的临床评估和神经认知评估,重点是注意力、记忆力和执行功能:结果:与健康对照组相比,ADHD 组在大多数临床和认知测量上都存在差异。与ADHD-HD患者相比,ADHD+HD患者表现出相似的ADHD症状,但主观冲动性、情绪和焦虑症状更强,功能障碍也更严重,注意力和执行功能障碍也更严重:结论:与不合并囤积症的ADHD患者相比,合并囤积症的ADHD患者表现出更复杂的临床和神经心理学表型,相关的功能障碍也更严重。这些结果进一步强调了评估和治疗成人多动症患者囤积行为的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The complex clinical and cognitive phenotype of adult patients with attention deficit hyperactivity disorder (ADHD) and comorbid hoarding disorder.

Objectives: Several studies consistently showed that patients with attention deficit hyperactivity disorder (ADHD) have high rates of hoarding disorder (HD) comorbidity. The aim of the present study was to compare the clinical and cognitive features of adult ADHD patients with and without hoarding comorbidity according to a self-report measure, and a sample of healthy controls.

Methods: Fifty-seven consecutive adult outpatients with a primary diagnosis of ADHD with comorbid hoarding disorder (ADHD+HD), 57 matched ADHD patients without hoarding disorder comorbidity (ADHD-HD), and a control group of 47 healthy controls (HCs) were enrolled. All subjects undergone a comprehensive clinical assessment and a neurocognitive assessment focused on attention, memory, and executive functions.

Results: The ADHD groups differed on most of the clinical and cognitive measures compared to HCs. ADHD+HD patients showed similar ADHD symptoms but greater subjective impulsivity, mood and anxiety symptoms, and a greater functional impairment compared to ADHD-HD patients as well as greater attentional and executive functioning impairments.

Conclusions: ADHD patients with comorbid hoarding disorder present a more complex clinical and neuropsychological phenotype correlated to a greater functional impairment compared to ADHD patients without this comorbidity. These results further highlight the relevance of assessing and treating hoarding behaviours in adults with ADHD.

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来源期刊
CiteScore
6.00
自引率
3.30%
发文量
42
审稿时长
>12 weeks
期刊介绍: International Journal of Psychiatry in Clinical Practice provides an international forum for communication among health professionals with clinical, academic and research interests in psychiatry. The journal gives particular emphasis to papers that integrate the findings of academic research into realities of clinical practice. Focus on the practical aspects of managing and treating patients. Essential reading for the busy psychiatrist, trainee and interested physician. Includes original research papers, comprehensive review articles and short communications. Key words: Psychiatry, Neuropsychopharmacology, Mental health, Neuropsychiatry, Clinical Neurophysiology, Psychophysiology, Psychotherapy, Addiction, Schizophrenia, Depression, Bipolar Disorders and Anxiety.
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