回放:在特定区域反向裂解锤头纹波酶可提高体内敲除效率。

IF 3 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
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引用次数: 0

摘要

撤回:Y. Peng, X. Ai, and B. Peng, "Trans-cleaving Hammerhead Ribozyme in Specific Regions Can Improve Knockdown Efficiency In Vivo," Journal of Cellular Biochemistry (Early View): https://doi.org/10.1002/jcb.30249.上述文章于 2022 年 4 月 11 日在线发表于 Wiley Online Library (wileyonlinelibrary.com),经作者、期刊主编 Christian Behl 和 Wiley Periodicals LLC 协议撤回。撤稿是应作者要求达成的,原因是文章中提供的数据令人担忧。作者承认在评估荧光强度时出现了重大失误,导致论文中介绍的系统的反向裂解效率数据不准确。他们还向期刊通报了免疫印迹检测结果中的错误。由于发现的错误影响了研究的整体结论,文章被撤回。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RETRACTION: Trans-Cleaving Hammerhead Ribozyme in Specific Regions Can Improve Knockdown Efficiency In Vivo.

Retraction: Y. Peng, X. Ai, and B. Peng, "Trans-cleaving Hammerhead Ribozyme in Specific Regions Can Improve Knockdown Efficiency In Vivo," Journal of Cellular Biochemistry (Early View): https://doi.org/10.1002/jcb.30249. The above article, published online on 11 April 2022 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed upon the authors' request due to concerns related to the data presented in the article. The authors admitted significant errors in the evaluation of the fluorescence intensity, resulting in inaccurate data on the trans-cleaving efficiency of the presented system. They also informed the journal of errors in the results of the immunoblot assays. As the identified errors affect the overall conclusions of the study, the article is retracted.

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来源期刊
Journal of cellular biochemistry
Journal of cellular biochemistry 生物-生化与分子生物学
CiteScore
9.90
自引率
0.00%
发文量
164
审稿时长
1 months
期刊介绍: The Journal of Cellular Biochemistry publishes descriptions of original research in which complex cellular, pathogenic, clinical, or animal model systems are studied by biochemical, molecular, genetic, epigenetic or quantitative ultrastructural approaches. Submission of papers reporting genomic, proteomic, bioinformatics and systems biology approaches to identify and characterize parameters of biological control in a cellular context are encouraged. The areas covered include, but are not restricted to, conditions, agents, regulatory networks, or differentiation states that influence structure, cell cycle & growth control, structure-function relationships.
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