老年髋部骨折年死亡率何时恢复到基线?

IF 1.6 4区 医学 Q2 SURGERY
Frontiers in Surgery Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI:10.3389/fsurg.2024.1359648
Joseph Bernstein, Alexander Lee, Jaimo Ahn
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引用次数: 0

摘要

背景:老年髋部骨折患者在受伤后死亡率很高。目前尚不清楚死亡率是否以及何时恢复到基线水平。因此,我们要问:老年髋部骨折的死亡率何时(如果有的话)恢复到整个人群的基线死亡率?老年髋部骨折后的死亡率与人群标准相比如何?了解这一时间表对于评估疾病负担和指导治疗计划至关重要:研究对象是退伍军人医疗保健系统中接受髋部骨折治疗的 17,868 名 65-89 岁男性患者。按照骨折时的年龄对患者进行分组,并在 10 年内每年评估一次特定年龄的分数生存率。作为对比对照组,建立了一个由 17,868 人组成的虚拟队列,该队列与患者组的年龄分布一致,并根据社会保障局的预期死亡率统计数据在 10 个周期内进行缩减:结果:骨折患者第一年的死亡率为 35.4%,而年龄匹配的对照组死亡率为 6.3%。到第十年,只有 8.5%的骨折患者仍然存活,而普通人群的这一比例为 39.8%。活过第一年的患者在随后所有年份中的年死亡风险始终在19%-21%之间:结论:初次受伤后存活下来的髋部骨折患者的年死亡风险仍高达约 20%,高于人群标准至少持续了十年。这些数据凸显了老年髋部骨折的严重性,并表明关注一两年的存活率可能无法完全反映损伤的严重性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
When does annual geriatric hip fracture mortality revert to baseline?

Background: Geriatric hip fracture patients exhibit high mortality post-injury. It's unclear if and when mortality reverts to baseline. We therefore ask, When, if ever, does the mortality rate of geriatric hip fracture revert to the population-wide baseline rate? How does the mortality rate after geriatric hip fracture compare to the population norms? Understanding this timeline is crucial for assessing disease burden and guiding treatment plans.

Methods: A cohort of 17,868 male patients aged 65-89 years treated for hip fracture within the VA healthcare system was studied. Patients were grouped by age at the time of fracture, and age-specific fractional survival was assessed annually for 10 years. For a comparison control group, a virtual cohort of 17,868 individuals, mirroring the age distribution of the patient group, was created and reduced over 10 cycles according to Social Security Administration expected mortality statistics.

Results: The year-one mortality rate among fracture patients was 35.4%, compared to 6.3% in age-matched controls. By year ten, only 8.5% of the fracture patients remained alive, vs. 39.8% in the general population. The annual risk of dying for patients who survived past the first year was consistently in the range 19%-21% for all subsequent years.

Conclusion: Hip fracture patients who survive the initial injury are still subject to annual mortality risk of approximately 20%, an elevation above population norms persisting for at least a decade. The data underscores the severity of geriatric hip fractures, and suggest that focusing one- or two-year survival rates may not fully capture the severity of the injury.

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来源期刊
Frontiers in Surgery
Frontiers in Surgery Medicine-Surgery
CiteScore
1.90
自引率
11.10%
发文量
1872
审稿时长
12 weeks
期刊介绍: Evidence of surgical interventions go back to prehistoric times. Since then, the field of surgery has developed into a complex array of specialties and procedures, particularly with the advent of microsurgery, lasers and minimally invasive techniques. The advanced skills now required from surgeons has led to ever increasing specialization, though these still share important fundamental principles. Frontiers in Surgery is the umbrella journal representing the publication interests of all surgical specialties. It is divided into several “Specialty Sections” listed below. All these sections have their own Specialty Chief Editor, Editorial Board and homepage, but all articles carry the citation Frontiers in Surgery. Frontiers in Surgery calls upon medical professionals and scientists from all surgical specialties to publish their experimental and clinical studies in this journal. By assembling all surgical specialties, which nonetheless retain their independence, under the common umbrella of Frontiers in Surgery, a powerful publication venue is created. Since there is often overlap and common ground between the different surgical specialties, assembly of all surgical disciplines into a single journal will foster a collaborative dialogue amongst the surgical community. This means that publications, which are also of interest to other surgical specialties, will reach a wider audience and have greater impact. The aim of this multidisciplinary journal is to create a discussion and knowledge platform of advances and research findings in surgical practice today to continuously improve clinical management of patients and foster innovation in this field.
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