Cristina Taliento , Gennaro Scutiero , Ginevra Battello , Alessia Sala , Giulia Pellecchia , Rita Trozzi , Martina Arcieri , Matteo Pavone , Nicolò Bizzarri , Pantaleo Greco , Lorenza Driul , Frédéric Amant , Anna Fagotti , Giovanni Scambia , Giuseppe Vizzielli , Stefano Restaino
{"title":"根据 FIGO 2018 分期系统对宫颈癌进行保胎治疗的生殖、产科和肿瘤学结果:系统综述。","authors":"Cristina Taliento , Gennaro Scutiero , Ginevra Battello , Alessia Sala , Giulia Pellecchia , Rita Trozzi , Martina Arcieri , Matteo Pavone , Nicolò Bizzarri , Pantaleo Greco , Lorenza Driul , Frédéric Amant , Anna Fagotti , Giovanni Scambia , Giuseppe Vizzielli , Stefano Restaino","doi":"10.1016/j.ejso.2024.109359","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>We assessed reproductive, obstetrical, and oncological outcomes in patients who underwent fertility-sparing treatment by including studies that adhere to the FIGO 2018 staging system.</div></div><div><h3>Methods</h3><div>Data on recurrence, mortality, pregnancy rate, live birth rate, and preterm delivery rate were collected.</div></div><div><h3>Results</h3><div>In patients with stages IA1, IA2, and IB1, the recurrence rate was 4.7 % and the death rate was 0.6 %. For patients with stage IB2, the recurrence rate was 12.1 % and the death rate was 3.2 %. Pregnancy rates for conization/simple trachelectomy and radical trachelectomy were 61.7 % and 50 %, respectively. A higher live birth rate (84.4 % vs 58.6 %), and lower preterm birth rate (18.3 % vs 33.3 %) were observed in patients undergoing conization compared to radical trachelectomy.</div></div><div><h3>Conclusion</h3><div>We found a recurrence rate of 4.7 % in patients with stage less than or equal to IB1 and 12.1 % in those with stage IB2. A higher rate of preterm delivery was observed in patients who underwent radical trachelectomy.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 1","pages":"Article 109359"},"PeriodicalIF":3.5000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reproductive, obstetrical and oncological outcomes of fertility-sparing treatment for cervical cancer according to the FIGO 2018 staging system: A systematic review\",\"authors\":\"Cristina Taliento , Gennaro Scutiero , Ginevra Battello , Alessia Sala , Giulia Pellecchia , Rita Trozzi , Martina Arcieri , Matteo Pavone , Nicolò Bizzarri , Pantaleo Greco , Lorenza Driul , Frédéric Amant , Anna Fagotti , Giovanni Scambia , Giuseppe Vizzielli , Stefano Restaino\",\"doi\":\"10.1016/j.ejso.2024.109359\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>We assessed reproductive, obstetrical, and oncological outcomes in patients who underwent fertility-sparing treatment by including studies that adhere to the FIGO 2018 staging system.</div></div><div><h3>Methods</h3><div>Data on recurrence, mortality, pregnancy rate, live birth rate, and preterm delivery rate were collected.</div></div><div><h3>Results</h3><div>In patients with stages IA1, IA2, and IB1, the recurrence rate was 4.7 % and the death rate was 0.6 %. For patients with stage IB2, the recurrence rate was 12.1 % and the death rate was 3.2 %. Pregnancy rates for conization/simple trachelectomy and radical trachelectomy were 61.7 % and 50 %, respectively. A higher live birth rate (84.4 % vs 58.6 %), and lower preterm birth rate (18.3 % vs 33.3 %) were observed in patients undergoing conization compared to radical trachelectomy.</div></div><div><h3>Conclusion</h3><div>We found a recurrence rate of 4.7 % in patients with stage less than or equal to IB1 and 12.1 % in those with stage IB2. A higher rate of preterm delivery was observed in patients who underwent radical trachelectomy.</div></div>\",\"PeriodicalId\":11522,\"journal\":{\"name\":\"Ejso\",\"volume\":\"51 1\",\"pages\":\"Article 109359\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ejso\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0748798324014276\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ejso","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0748798324014276","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Reproductive, obstetrical and oncological outcomes of fertility-sparing treatment for cervical cancer according to the FIGO 2018 staging system: A systematic review
Objective
We assessed reproductive, obstetrical, and oncological outcomes in patients who underwent fertility-sparing treatment by including studies that adhere to the FIGO 2018 staging system.
Methods
Data on recurrence, mortality, pregnancy rate, live birth rate, and preterm delivery rate were collected.
Results
In patients with stages IA1, IA2, and IB1, the recurrence rate was 4.7 % and the death rate was 0.6 %. For patients with stage IB2, the recurrence rate was 12.1 % and the death rate was 3.2 %. Pregnancy rates for conization/simple trachelectomy and radical trachelectomy were 61.7 % and 50 %, respectively. A higher live birth rate (84.4 % vs 58.6 %), and lower preterm birth rate (18.3 % vs 33.3 %) were observed in patients undergoing conization compared to radical trachelectomy.
Conclusion
We found a recurrence rate of 4.7 % in patients with stage less than or equal to IB1 and 12.1 % in those with stage IB2. A higher rate of preterm delivery was observed in patients who underwent radical trachelectomy.
期刊介绍:
JSO - European Journal of Surgical Oncology ("the Journal of Cancer Surgery") is the Official Journal of the European Society of Surgical Oncology and BASO ~ the Association for Cancer Surgery.
The EJSO aims to advance surgical oncology research and practice through the publication of original research articles, review articles, editorials, debates and correspondence.