长时间步行对 2 型糖尿病患者空腹血浆葡萄糖的影响：随机对照交叉研究。

IF 3.2 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Diabetic Medicine Pub Date : 2024-11-09 DOI:10.1111/dme.15468

Anxious J Niwaha, Beverley M Shields, Lauren R Rodgers, Andrew T Hattersley, Robert C Andrews, Moffat J Nyirenda, Angus G Jones

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引用次数: 0

摘要

目的：在许多低收入国家，空腹血糖是监测血糖控制的主要指标。在这些国家，许多患者步行很远的距离去就诊，但步行对 2 型糖尿病患者空腹血糖的影响尚不清楚。我们旨在确定步行对 2 型糖尿病患者空腹血糖的影响：方法：在一项随机交叉试验中，比较了 2 型糖尿病患者在跑步机上以 4.5 公里/小时的预定速度步行 1 小时与不步行（静止）之间在空腹状态下血糖与基线相比的变化：总共有 45 人参加，全部完成了两次访问；21/45（46.7%）为女性，年龄中位数为 51 岁。步行时和步行后的血糖与休息时的血糖相似；1 小时和 2 小时的血糖差异（步行减去休息）分别为-0.15（95% CI：-0.55，0.26）和-0.10（95% CI：-0.50，0.31）毫摩尔/升，两者的 p > 0.4：2型糖尿病患者长时间步行不会对空腹血浆葡萄糖产生有意义的影响；因此，在步行就诊的患者中，空腹血糖监测血糖负担的可靠性不太可能发生改变。

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The impact of prolonged walking on fasting plasma glucose in type 2 diabetes: A randomised controlled crossover study.

Aims: In many low-income countries, fasting glucose is the primary measure for monitoring glycaemic control. Many patients in these countries walk long distances to the clinic, but the impact of walking on fasting glucose in type 2 diabetes is unknown. We aimed to determine the impact of walking on fasting glucose in people with type 2 diabetes.

Methods: In a randomised crossover trial, the change in glucose from baseline in the fasting state was compared between walking on a treadmill at a predetermined speed of 4.5 km/h for 1 h and not walking (resting) in people with type 2 diabetes.

Results: In all, 45 participants were enrolled and all completed both visits; 21/45 (46.7%) were women, and the median age was 51. Glucose during and after walking was similar to glucose while at rest; the glucose difference (walking minus rest) was -0.15 (95% CI: -0.55, 0.26) and -0.10 (95% CI: -0.50, 0.31) mmol/L at 1 and 2 h, respectively, p > 0.4 for both.

Conclusions: Fasting plasma glucose is not meaningfully affected by prolonged walking in participants with type 2 diabetes; therefore, the reliability of fasting glucose for monitoring glycaemic burden is unlikely to be altered in patients who walk to the clinic.

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来源期刊

Diabetic Medicine 医学-内分泌学与代谢

CiteScore

7.20

自引率

5.70%

发文量

229

审稿时长

3-6 weeks

期刊介绍： Diabetic Medicine, the official journal of Diabetes UK, is published monthly simultaneously, in print and online editions. The journal publishes a range of key information on all clinical aspects of diabetes mellitus, ranging from human genetic studies through clinical physiology and trials to diabetes epidemiology. We do not publish original animal or cell culture studies unless they are part of a study of clinical diabetes involving humans. Categories of publication include research articles, reviews, editorials, commentaries, and correspondence. All material is peer-reviewed. We aim to disseminate knowledge about diabetes research with the goal of improving the management of people with diabetes. The journal therefore seeks to provide a forum for the exchange of ideas between clinicians and researchers worldwide. Topics covered are of importance to all healthcare professionals working with people with diabetes, whether in primary care or specialist services. Surplus generated from the sale of Diabetic Medicine is used by Diabetes UK to know diabetes better and fight diabetes more effectively on behalf of all people affected by and at risk of diabetes as well as their families and carers.”