Vincent Vakaet, Hans Van Hulle, Renée De Noyette, Max Schoepen, Pieter Deseyne, Vincent Huybrechts, Els Van Caelenberg, Annick Van Greveling, Chris Monten, Luc De Baerdemaeker, Wilfried De Neve, Marc Coppens, Liv Veldeman
{"title":"在乳腺癌照射过程中,使用高流量鼻氧预吸氧和自主过度换气,尽量缩短反复长时间深吸气屏气的准备时间。","authors":"Vincent Vakaet, Hans Van Hulle, Renée De Noyette, Max Schoepen, Pieter Deseyne, Vincent Huybrechts, Els Van Caelenberg, Annick Van Greveling, Chris Monten, Luc De Baerdemaeker, Wilfried De Neve, Marc Coppens, Liv Veldeman","doi":"10.1093/bjr/tqae223","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Deep inspiration breath-holds (DIBHs) reduce heart and lung toxicity during breast cancer radiotherapy. Consecutive DIBHs are stressful, time-consuming, and leads to position changes. To facilitate the introduction of pre-oxygenation using high-flow nasal oxygen (HFNO) and hyperventilation to prolong DIBHs (L-DIBHs), we examined the effect of hyperventilation time on the duration of L-DIBHs. Additionally, to minimize total treatment time, the feasibility of several successive L-DIBHs was examined.</p><p><strong>Methods: </strong>Our previous protocol imposed 3 min of hyperventilation at 16 breaths per minute with pre-oxygenation using HFNO, in prone position. In the first phase, the effect of hyperventilation time on the length of the L-DIBH was investigated. The aim of the second phase was to investigate the feasibility of shorter preparation times before the second and third L-DIBH in the case of 3 consecutive L-DIBHs of at least 2 minutes.</p><p><strong>Results: </strong>There is a positive but weak correlation between preparation time and L-DIBH duration. With either 3 minutes 30 seconds or 6 minutes 20 seconds (depending on fitness) of voluntary hyperventilation duration, 93% of subjects could hold 3 consecutive L-DIBHs for over 2 minutes. The median duration of the third and last L-DIBH was 3 minutes 17 seconds (SD 1 min 4 seconds).</p><p><strong>Conclusion: </strong>A weak relationship exists between the hyperventilation time and L-DIBH duration. Repeating L-DIBHs with shorter preparations is achievable, resulting in a shorter total treatment time required.</p><p><strong>Advances in knowledge: </strong>It is possible to perform repeated L-DIBHs for breast cancer irradiation using HFNO and hyperventilation.</p>","PeriodicalId":9306,"journal":{"name":"British Journal of Radiology","volume":" ","pages":"45-49"},"PeriodicalIF":1.8000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Minimizing preparation time for repeated prolonged deep-inspiration breath holds during breast cancer irradiation using pre-oxygenation with high-flow nasal oxygen and voluntary hyperventilation.\",\"authors\":\"Vincent Vakaet, Hans Van Hulle, Renée De Noyette, Max Schoepen, Pieter Deseyne, Vincent Huybrechts, Els Van Caelenberg, Annick Van Greveling, Chris Monten, Luc De Baerdemaeker, Wilfried De Neve, Marc Coppens, Liv Veldeman\",\"doi\":\"10.1093/bjr/tqae223\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Deep inspiration breath-holds (DIBHs) reduce heart and lung toxicity during breast cancer radiotherapy. Consecutive DIBHs are stressful, time-consuming, and leads to position changes. To facilitate the introduction of pre-oxygenation using high-flow nasal oxygen (HFNO) and hyperventilation to prolong DIBHs (L-DIBHs), we examined the effect of hyperventilation time on the duration of L-DIBHs. Additionally, to minimize total treatment time, the feasibility of several successive L-DIBHs was examined.</p><p><strong>Methods: </strong>Our previous protocol imposed 3 min of hyperventilation at 16 breaths per minute with pre-oxygenation using HFNO, in prone position. In the first phase, the effect of hyperventilation time on the length of the L-DIBH was investigated. The aim of the second phase was to investigate the feasibility of shorter preparation times before the second and third L-DIBH in the case of 3 consecutive L-DIBHs of at least 2 minutes.</p><p><strong>Results: </strong>There is a positive but weak correlation between preparation time and L-DIBH duration. With either 3 minutes 30 seconds or 6 minutes 20 seconds (depending on fitness) of voluntary hyperventilation duration, 93% of subjects could hold 3 consecutive L-DIBHs for over 2 minutes. The median duration of the third and last L-DIBH was 3 minutes 17 seconds (SD 1 min 4 seconds).</p><p><strong>Conclusion: </strong>A weak relationship exists between the hyperventilation time and L-DIBH duration. Repeating L-DIBHs with shorter preparations is achievable, resulting in a shorter total treatment time required.</p><p><strong>Advances in knowledge: </strong>It is possible to perform repeated L-DIBHs for breast cancer irradiation using HFNO and hyperventilation.</p>\",\"PeriodicalId\":9306,\"journal\":{\"name\":\"British Journal of Radiology\",\"volume\":\" \",\"pages\":\"45-49\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/bjr/tqae223\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/bjr/tqae223","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Minimizing preparation time for repeated prolonged deep-inspiration breath holds during breast cancer irradiation using pre-oxygenation with high-flow nasal oxygen and voluntary hyperventilation.
Objectives: Deep inspiration breath-holds (DIBHs) reduce heart and lung toxicity during breast cancer radiotherapy. Consecutive DIBHs are stressful, time-consuming, and leads to position changes. To facilitate the introduction of pre-oxygenation using high-flow nasal oxygen (HFNO) and hyperventilation to prolong DIBHs (L-DIBHs), we examined the effect of hyperventilation time on the duration of L-DIBHs. Additionally, to minimize total treatment time, the feasibility of several successive L-DIBHs was examined.
Methods: Our previous protocol imposed 3 min of hyperventilation at 16 breaths per minute with pre-oxygenation using HFNO, in prone position. In the first phase, the effect of hyperventilation time on the length of the L-DIBH was investigated. The aim of the second phase was to investigate the feasibility of shorter preparation times before the second and third L-DIBH in the case of 3 consecutive L-DIBHs of at least 2 minutes.
Results: There is a positive but weak correlation between preparation time and L-DIBH duration. With either 3 minutes 30 seconds or 6 minutes 20 seconds (depending on fitness) of voluntary hyperventilation duration, 93% of subjects could hold 3 consecutive L-DIBHs for over 2 minutes. The median duration of the third and last L-DIBH was 3 minutes 17 seconds (SD 1 min 4 seconds).
Conclusion: A weak relationship exists between the hyperventilation time and L-DIBH duration. Repeating L-DIBHs with shorter preparations is achievable, resulting in a shorter total treatment time required.
Advances in knowledge: It is possible to perform repeated L-DIBHs for breast cancer irradiation using HFNO and hyperventilation.
期刊介绍:
BJR is the international research journal of the British Institute of Radiology and is the oldest scientific journal in the field of radiology and related sciences.
Dating back to 1896, BJR’s history is radiology’s history, and the journal has featured some landmark papers such as the first description of Computed Tomography "Computerized transverse axial tomography" by Godfrey Hounsfield in 1973. A valuable historical resource, the complete BJR archive has been digitized from 1896.
Quick Facts:
- 2015 Impact Factor – 1.840
- Receipt to first decision – average of 6 weeks
- Acceptance to online publication – average of 3 weeks
- ISSN: 0007-1285
- eISSN: 1748-880X
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