B(C6F5)3助催化剂促进格拉布斯 I 的非常规卤化物萃取，从而提高反应活性并限制分解。

IF 2.5 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Organometallics Pub Date : 2024-10-23 eCollection Date: 2024-11-11 DOI:10.1021/acs.organomet.4c00178

Austin W Medley, Diya Patel, Calvin Utne, Trandon A Bender

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引用次数: 0

摘要

基于钌的格拉布斯复分解反应已成为合成化学家的常见反应。从 Grubbs I (GI) 发展而来的新一代催化剂具有更高的稳定性、官能团兼容性和更优越的反应活性。然而，这些进步也导致了成本的增加。为此，我们在此报告如何通过添加市售的三（五氟苯基）硼烷路易斯酸（其本身已成为一种常用催化剂）来提高 Grubbs I 的反应活性。此外，反应活性的提高是通过卤化物抽取而非传统的膦解离产生的，从而提供了不同于不使用路易斯酸助催化剂合成的开环偏聚聚合产物。

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B(C₆F₅)₃ Co-Catalyst Promotes Unconventional Halide Abstraction from Grubbs I to Enhance Reactivity and Limit Decomposition.

Ruthenium based Grubbs metathesis has become a commonplace reaction for synthetic chemists. Development of new generations of catalysts evolving from Grubbs I (GI) have led to greater stability, functional group compatibility, and superior reactivities. However, these advancements lead to increased costs. To this end, we report here how the addition of the commercially available tris(pentafluorophenyl)borane Lewis acid, which has become a common place catalyst in its own right, leads to enhanced reactivity of GI. Moreover, the increased reactivity arises via halide abstraction rather than traditional phosphine dissociation, providing ring-opening metathesis polymerization products that are divergent from those synthesized without the Lewis acid cocatalyst.

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来源期刊

Organometallics 化学-无机化学与核化学

CiteScore

5.60

自引率

7.10%

发文量

382

审稿时长

1.7 months

期刊介绍： Organometallics is the flagship journal of organometallic chemistry and records progress in one of the most active fields of science, bridging organic and inorganic chemistry. The journal publishes Articles, Communications, Reviews, and Tutorials (instructional overviews) that depict research on the synthesis, structure, bonding, chemical reactivity, and reaction mechanisms for a variety of applications, including catalyst design and catalytic processes; main-group, transition-metal, and lanthanide and actinide metal chemistry; synthetic aspects of polymer science and materials science; and bioorganometallic chemistry.