一例接种破伤风-白喉-百日咳-脑膜炎球菌疫苗后出疹的病例。

IF 2.6 3区医学 Q2 ALLERGY

Allergy and asthma proceedings Pub Date : 2024-11-01 DOI:10.2500/aap.2024.45.240083

Leonardo Salazar, Joanne Acevedo, Fiona Adame, Brent Kelly, Cleavon Covington

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引用次数: 0

摘要

我们为您介绍一例 12 岁健康女孩的病例，她在发病初期出现干燥、色素沉着和隆起的瘙痒性皮疹。皮损最初出现在她的大腿上，在接种破伤风-白喉-百日咳（Tdap）和脑膜炎球菌疫苗数小时后，皮损发展到躯干和手臂。在对中等药效的局部类固醇反应不佳后，我们对她进行了活组织检查，最终确诊了她的病情。据目前的文献报道，接种百白破疫苗、麻疹、腮腺炎和风疹疫苗以及 COVID-19 疫苗后会出现这种情况，但据我们所知，接种脑膜炎疫苗后不会出现这种情况。疫苗在病理生理学中的作用尚不清楚。这种情况可能会被误认为是过敏反应，从而导致避免接种疫苗。

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A case of a rash after tetanus-diphtheria-pertussis and meningococcal vaccination.

We present a case of a 12-year-old healthy girl who presented with acute onset of dry, hyperpigmented, and raised pruritic rash. The lesions initially presented on her thighs then progressed to the trunk and arms hours after receiving the tetanus-diphtheria-pertussis (Tdap) and meningococcal vaccine. After a poor response to medium potency topical steroids, a biopsy specimen was taken, which led to our diagnosis. Current literature reports this condition occurring after Tdap; measles, mumps, and rubella; and COVID-19 vaccinations; but, to our knowledge, not after meningitis vaccines. The role that vaccines play in the pathophysiology remains unclear. This condition may get mistaken for an allergic reaction and lead to vaccine avoidance.

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来源期刊

Allergy and asthma proceedings 医学-过敏

CiteScore

5.70

自引率

35.70%

发文量

106

审稿时长

6-12 weeks

期刊介绍： Allergy & Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists. The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma. Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.