基于天然材料的水凝胶用于术后化疗的最新进展。

IF 5.4 2区医学 Q1 BIOPHYSICS

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-11-12 DOI:10.1016/j.colsurfb.2024.114375

Chang Li , Xiaocong Li , Xinping Liu , Li Yuan , Xiao Duan , Wei Guo

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引用次数: 0

摘要

与全身化疗相比，水凝胶具有副作用小、药物作用时间长等优点，已被广泛用于术后原位化疗。本文综述了基于天然材料的水凝胶在肿瘤切除术后的应用，探讨其作为术后化疗的一种选择。研究并总结了不同材料基水凝胶、不同反应基水凝胶以及植入式、注射式和喷雾式水凝胶的临床应用。在主要内容的基础上，我们报告了基于水凝胶的局部给药系统可能的临床应用前景和典型功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Recent progress of natural materials-based hydrogel for postoperative chemotherapy

Hydrogels have been widely used for in situ postoperative chemotherapy due to fewer side effects and longer duration of drug action compared to systemic chemotherapy. This paper reviews the application of natural materials-based hydrogels after tumor resection to explore them as an option for postoperative chemotherapy. Different material-based hydrogels, different response-based hydrogels, and the clinical applications of implantable, injectable, and sprayed hydrogels were investigated and summarized. Based on the main content, we report the possible clinical application prospects and typical functions of hydrogel-based local drug delivery systems.

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来源期刊

Colloids and Surfaces B: Biointerfaces 生物-材料科学：生物材料

CiteScore

11.10

自引率

3.40%

发文量

730

审稿时长

42 days

期刊介绍： Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields. Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication. The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.