在牙科环境中识别亚裔人群中未确诊的糖尿病和糖尿病前期--临床风险模型

IF 5.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Hoe Kit Chee, Frank Abbas, Arie Jan van Winkelhoff, Geerten Has Tjakkes, Hla Myint Htoon, Huihua Li, Yvonne de Waal, Arjan Vissink, Chaminda Jayampath Seneviratne
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引用次数: 0

摘要

材料与方法 共有 1074 名参与者完成了糖尿病风险测试问卷、全口牙周检查和点测式 HbA1c 手指采血测试。以确诊糖尿病为结果,采用单变量逻辑回归评估潜在因素对预测糖尿病的影响。结果 1074 名参与者中分别有 65 人(6.1%)和 83 人(7.7%)被医学证实患有 T2DM 和糖尿病前期。糖尿病的 "最佳 "预测风险模型包括体重指数(BMI)、糖尿病家族史、吸烟和 III/IV 期或严重牙周炎诊断,其曲线下面积(AUC)分别为 0.717(95% 置信区间,CI [0.689-0.744])和 0.721(95% CI [0.693-0.748])。结论 临床诊断出患有晚期牙周炎并伴有高体重指数(BMI)、阳性糖尿病家族史和吸烟的牙科患者可能是糖尿病的高危人群,应进行糖尿病筛查并转诊进行医学确认和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Identifying Undiagnosed Diabetes and Prediabetes in the Dental Setting in an Asian Population—A Clinical Risk Model
AimTo assess the glycaemic status of Asian patients in a tertiary care dental setting and develop a risk model for undiagnosed diabetes mellitus (DM).Material and MethodsA total of 1074 participants completed a diabetes risk test questionnaire, full‐mouth periodontal examination and a point‐of‐care HbA1c finger‐prick blood test. Univariable logistic regression was performed to assess the effect of potential factors to predict DM, with confirmed diabetes as the outcome. Subsequently, multivariable logistic regression analysis with stepwise variable selection was employed to develop the final models for predicting DM.ResultsSixty‐five (6.1%) and 83 (7.7%) of the 1074 participants were medically confirmed with T2DM and prediabetes, respectively. The ‘best’ predictive risk model for DM included body mass index (BMI), family history of diabetes, smoking and a diagnosis of Stage III/IV or severe periodontitis with an area under the curve (AUC) of 0.717 (95% confidence interval, CI [0.689–0.744]) and 0.721 (95% CI [0.693–0.748]), respectively. Including the oral health measure marginally increased the AUC.ConclusionsDental patients clinically diagnosed with advanced periodontitis in combination with high BMI, positive family history of DM and smoking are potentially at high risk for DM and should be screened for DM and referred for medical confirmation and management.
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来源期刊
Journal of Clinical Periodontology
Journal of Clinical Periodontology 医学-牙科与口腔外科
CiteScore
13.30
自引率
10.40%
发文量
175
审稿时长
3-8 weeks
期刊介绍: Journal of Clinical Periodontology was founded by the British, Dutch, French, German, Scandinavian, and Swiss Societies of Periodontology. The aim of the Journal of Clinical Periodontology is to provide the platform for exchange of scientific and clinical progress in the field of Periodontology and allied disciplines, and to do so at the highest possible level. The Journal also aims to facilitate the application of new scientific knowledge to the daily practice of the concerned disciplines and addresses both practicing clinicians and academics. The Journal is the official publication of the European Federation of Periodontology but wishes to retain its international scope. The Journal publishes original contributions of high scientific merit in the fields of periodontology and implant dentistry. Its scope encompasses the physiology and pathology of the periodontium, the tissue integration of dental implants, the biology and the modulation of periodontal and alveolar bone healing and regeneration, diagnosis, epidemiology, prevention and therapy of periodontal disease, the clinical aspects of tooth replacement with dental implants, and the comprehensive rehabilitation of the periodontal patient. Review articles by experts on new developments in basic and applied periodontal science and associated dental disciplines, advances in periodontal or implant techniques and procedures, and case reports which illustrate important new information are also welcome.
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