TAVI 手术中的血管并发症:评估、管理和结果--一项回顾性研究。

IF 2.7 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Cheilas Vasileios, Kosmas Ilias, Filandrianos George, Smparouni Eutyxia, Leontiadis Euaggelos, Martinos Antonios, Papadis Athanasios, Malakos Ioannis, Saplaouras Athanasios, Kostopoulou Anna, Konstantinos Letsas, Panayiota Georgiadou, Voudris Vasileios, Michalis Efremidis, Iakovou Ioannis
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引用次数: 0

摘要

背景:经导管主动脉瓣植入术(TAVI)已成为治疗主动脉瓣狭窄的重要方法,主要用于老年人群。尽管在临床上取得了成功,但 TAVI 期间血管并发症的发生率和影响仍是一个令人严重关切的问题:方法:我们对 1,343 例 TAVI 手术中出现血管并发症的 140 例患者进行了回顾性分析。对患者的人口统计学特征、临床特征和手术特征进行了仔细研究。通过各种诊断方法确定了术中和术后的血管并发症。统计分析用于确定关联性和显著性水平。研究还与国际文献进行了比较评估,以获得更广泛的见解:研究显示,血管并发症的总发生率约为 10.44%。冠状动脉疾病(CAD)-p-值(0.013)、瓣膜类型选择-p-值(0.016)和入路点-p-值(0.027)与这些并发症有显著相关性。TAVI 手术的并发症发生率包括假性动脉瘤(4.76%)、动静脉瘘(1.49%)、血肿(0.37%)、解剖(2.24%)、动脉穿孔(0.15%)、狭窄/闭塞(0.37%)和闭合装置故障(1.94%)。在瓣膜入口处发生的并发症中,70%以上是由解剖和闭合装置故障引起的,而70%以上的假性动脉瘤主要与辫子入口处有关。出现血管并发症的患者住院时间延长(7.84 ±SD 3.14),强调了术后护理警惕性的重要性:本研究对TAVI手术中的血管并发症进行了全面深入的研究,揭示了血管并发症的发生率、风险因素、临床表现、诊断方法和管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vascular complications in TAVI procedures: assessment, management, and outcomes-a retrospective study.

Objective: Transcatheter Aortic Valve Implantation (TAVI) has emerged as a pivotal therapeutic modality for aortic stenosis, predominantly in the elderly population. Despite its clinical success, the incidence and implications of vascular complications during TAVI remain a subject of critical concern.

Methods: A retrospective analysis was conducted on 140 patients who experienced vascular complications during TAVI procedures from a total cohort of 1343 cases. Patient demographics, clinical profiles, and procedural characteristics were scrupulously examined. Vascular complications, both intraoperative and postoperative, were identified through various diagnostic modalities. Statistical analyses were employed to discern associations and significance levels. Comparative assessments with international literature were performed to gain broader insights.

Results: The study unveiled an overall incidence of vascular complications at approximately 10.44%. Coronary Artery Disease (CAD)-p-value (0.013), choice of valve type-p-value (0.016), and access point-p-value (0.027) demonstrated significant correlations with these complications. Complication incidences in TAVI procedures included pseudoaneurysms (4.76%), arteriovenous fistulas (1.49%), hematomas (0.37%), dissections (2.24%), arterial perforations (0.15%), stenosis/occlusion (0.37%), and closure device failures (1.94%). Over 70% of complications at the valve entry point result from dissections and closure device failures, while the pigtail entry point is predominantly linked to over 70% of pseudoaneurysms. Extended hospitalization (7.84 ± SD 3.14) was observed for patients experiencing vascular complications, underlining the importance of vigilant postprocedural care.

Conclusion: This study provides comprehensive insights into vascular complications during TAVI procedures, shedding light on their incidence, risk factors, clinical presentations, diagnostic methodologies, and management strategies.

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来源期刊
Hellenic Journal of Cardiology
Hellenic Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.90
自引率
7.30%
发文量
86
审稿时长
56 days
期刊介绍: The Hellenic Journal of Cardiology (International Edition, ISSN 1109-9666) is the official journal of the Hellenic Society of Cardiology and aims to publish high-quality articles on all aspects of cardiovascular medicine. A primary goal is to publish in each issue a number of original articles related to clinical and basic research. Many of these will be accompanied by invited editorial comments. Hot topics, such as molecular cardiology, and innovative cardiac imaging and electrophysiological mapping techniques, will appear frequently in the journal in the form of invited expert articles or special reports. The Editorial Committee also attaches great importance to subjects related to continuing medical education, the implementation of guidelines and cost effectiveness in cardiology.
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