{"title":"利用儿科网格型参考计算模型估算和分析 131I 的 S 值。","authors":"Pradeep Kumar Singh, Hemant Kumar Patni, Deepak Kumar Akar, Pramilla D Sawant","doi":"10.1088/1361-6498/ad8fb8","DOIUrl":null,"url":null,"abstract":"<p><p>This study examines the effect of paediatric mesh-type reference computational phantoms on organ<i>S</i>values resulting from radioiodine (<sup>131</sup>I) intake. Using Geant4, we estimated<sup>131</sup>I<i>S</i>values for 30 radiosensitive target tissues due to emission from the thyroid (Target ← Thyroid) in these phantoms. Our results show that<i>S</i>values differ between male and female phantoms of the same age and<i>S</i>values also decrease as phantom age increases. The male-to-female<i>S</i>value ratio typically varies within 10%, with larger differences observed for the esophagus, extra-thoracic regions, muscles, bladder, and sex organs. On average,<i>S</i>values for mesh phantoms are approximately 17% higher than those for voxel phantoms, with larger discrepancies for organs remodelled separately in mesh phantoms. The study provides organ<i>S</i>values for the paediatric population due to<sup>131</sup>I exposure from the thyroid, based on the reference mesh-type computational phantoms, enhancing organ dose estimation in emergency situations and during radioiodine treatment.</p>","PeriodicalId":50068,"journal":{"name":"Journal of Radiological Protection","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Estimation and analysis of<i>S</i>values for<sup>131</sup>I using paediatric mesh type reference computational phantoms.\",\"authors\":\"Pradeep Kumar Singh, Hemant Kumar Patni, Deepak Kumar Akar, Pramilla D Sawant\",\"doi\":\"10.1088/1361-6498/ad8fb8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study examines the effect of paediatric mesh-type reference computational phantoms on organ<i>S</i>values resulting from radioiodine (<sup>131</sup>I) intake. Using Geant4, we estimated<sup>131</sup>I<i>S</i>values for 30 radiosensitive target tissues due to emission from the thyroid (Target ← Thyroid) in these phantoms. Our results show that<i>S</i>values differ between male and female phantoms of the same age and<i>S</i>values also decrease as phantom age increases. The male-to-female<i>S</i>value ratio typically varies within 10%, with larger differences observed for the esophagus, extra-thoracic regions, muscles, bladder, and sex organs. On average,<i>S</i>values for mesh phantoms are approximately 17% higher than those for voxel phantoms, with larger discrepancies for organs remodelled separately in mesh phantoms. The study provides organ<i>S</i>values for the paediatric population due to<sup>131</sup>I exposure from the thyroid, based on the reference mesh-type computational phantoms, enhancing organ dose estimation in emergency situations and during radioiodine treatment.</p>\",\"PeriodicalId\":50068,\"journal\":{\"name\":\"Journal of Radiological Protection\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Radiological Protection\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://doi.org/10.1088/1361-6498/ad8fb8\",\"RegionNum\":4,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Radiological Protection","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1088/1361-6498/ad8fb8","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
本研究探讨了儿科网状参考计算模型对摄入放射性碘(131I)导致的器官 S 值的影响。我们使用 Geant4 估算了这些模型中甲状腺(目标←甲状腺)发射的 30 个放射敏感靶组织的 131I S 值。结果表明,同年龄的男性和女性人体模型的 S 值不同,而且随着人体模型年龄的增加,S 值也会降低。男性与女性的 S 值比率通常在 10%以内,食道、胸腔外区域、肌肉、膀胱和性器官的 S 值差异较大。平均而言,网状模型的 S 值比体素模型高出约 17%,网状模型中单独重塑器官的 S 值差异更大。该研究基于参考网格型计算模型,为儿科人群提供了甲状腺131I照射的器官S值,从而提高了紧急情况下和放射性碘治疗期间的器官剂量估算。
Estimation and analysis ofSvalues for131I using paediatric mesh type reference computational phantoms.
This study examines the effect of paediatric mesh-type reference computational phantoms on organSvalues resulting from radioiodine (131I) intake. Using Geant4, we estimated131ISvalues for 30 radiosensitive target tissues due to emission from the thyroid (Target ← Thyroid) in these phantoms. Our results show thatSvalues differ between male and female phantoms of the same age andSvalues also decrease as phantom age increases. The male-to-femaleSvalue ratio typically varies within 10%, with larger differences observed for the esophagus, extra-thoracic regions, muscles, bladder, and sex organs. On average,Svalues for mesh phantoms are approximately 17% higher than those for voxel phantoms, with larger discrepancies for organs remodelled separately in mesh phantoms. The study provides organSvalues for the paediatric population due to131I exposure from the thyroid, based on the reference mesh-type computational phantoms, enhancing organ dose estimation in emergency situations and during radioiodine treatment.
期刊介绍:
Journal of Radiological Protection publishes articles on all aspects of radiological protection, including non-ionising as well as ionising radiations. Fields of interest range from research, development and theory to operational matters, education and training. The very wide spectrum of its topics includes: dosimetry, instrument development, specialized measuring techniques, epidemiology, biological effects (in vivo and in vitro) and risk and environmental impact assessments.
The journal encourages publication of data and code as well as results.