Exploring the correlation between dietary zinc intake and stroke risk in adults based on NHANES database.

Objective: To explore the relationship between dietary zinc intake and stroke.

Methods: Subjects from the National Health and Nutrition Examination Survey (NHANES) database (2015 to 2020) were included. Zinc intake was determined using two 24-h dietary recall interviews, and stroke was determined using the Medical Condition Questionnaire (MCQ). Logistic analysis was used to analyze the association between zinc intake and stroke risk. 1:1 nearest neighbor propensity score matching (PSM) was used to reduce selection bias.

Results: 4705 subjects were included in the study. Multivariate logistic regression analysis before and after matching showed that increased zinc intake was associated with a reduced risk of stroke. And as zinc intake increases, the risk of stroke shows a gradually decreasing trend. Compared with the Q1 group, the risk of stroke in the Q2, Q3, and Q4 groups was reduced by approximately 0.27 times, 0.29 times, and 0.31 times respectively. And there is no interaction between dietary zinc intake and gender in stroke patients.

Conclusion: Dietary zinc intake may be a protective factor against stroke, and increasing its intake may prevent or reduce the symptoms of stroke and related diseases.