甲氧苄啶-磺胺甲噁唑（TMP-SMZ）和依拉韦西林联合疗法治疗伊丽莎白金格anophelis引发的肺部感染：病例报告。

IF 2.9 3区医学 Q2 INFECTIOUS DISEASES

Infection and Drug Resistance Pub Date : 2024-11-03 eCollection Date: 2024-01-01 DOI:10.2147/IDR.S490902

Qimei Wei, Wenxia Zuo, Rong Cong, Kun Luo, Shanshan Dong

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引用次数: 0

摘要

伊丽莎白金格氏菌（Elizabethkingia anophelis）是一种机会性病原体，可导致严重的危及生命的感染。在本报告中，我们描述了一例年轻女性患者在接受心脏手术后由阿诺螺旋体引起的肺部感染，该患者在接受三甲双胍-磺胺甲噁唑（TMP-SMZ）和依拉维辛联合治疗后获得成功。此外，本报告还总结了阿诺螺旋体感染的高危因素、临床表现和治疗方案。鉴于该病菌对抗菌药物的高度耐药性，以及不恰当的经验性抗菌治疗是导致死亡的一个风险因素，我们的病例对类似病例具有重要的参考价值，并强调了有效治疗的潜在策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Combination Therapy of Trimethoprim-Sulfamethoxazole (TMP-SMZ) and Eravacycline for Treating Elizabethkingia anophelis-Induced Pulmonary Infections: A Case Report.

Elizabethkingia anophelis is an opportunistic pathogen that causes serious life-threatening infections. In this report, we describe a case of pulmonary infection caused by E. anophelis in a young female patient, following cardiac surgery, which was successfully treated with a combination of trimethoprim-sulfamethoxazole (TMP-SMZ) and eravacycline. Additionally, this report provides a summary of high-risk factors for E. anophelis infection, clinical manifestations, and therapeutic options. Given the high degree of antimicrobial drug resistance of the organism and the fact that inappropriate empirical antimicrobial therapy constitutes a risk factor for mortality, our case serves as a valuable reference for similar cases, highlighting potential strategies for effective management.

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来源期刊

Infection and Drug Resistance Medicine-Pharmacology (medical)

CiteScore

5.60

自引率

7.70%

发文量

826

审稿时长

16 weeks

期刊介绍： About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.