报纸背后的人--古川沙耶、佐藤明和森下义弘。

IF 3.7 2区 生物学 Q1 DEVELOPMENTAL BIOLOGY
Development Pub Date : 2024-11-01 Epub Date: 2024-11-08 DOI:10.1242/dev.204443
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引用次数: 0

摘要

肢体再生的一个显著特点是能够再生出正常的肢体形态和解剖模式。尽管人们认为再生使用的机制与发育过程中使用的机制相似,但对于如何在囊泡大小不同的情况下实现再生还不甚了解。在一项新的研究中,Akira Satoh、Yoshihiro Morishita及其同事研究了腋蛙胚泡大小的等比级数以及关键基因相对于残肢大小的表达模式。为了进一步了解这项工作,我们采访了这项研究的第一作者古川沙也(Saya Furukawa)、通讯作者、冈山大学教授佐藤彰(Akira Satoh)和日本理化学研究所首席研究员森下义弘(Yoshihiro Morishita)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The people behind the papers - Saya Furukawa, Akira Satoh and Yoshihiro Morishita.

A remarkable feature of limb regeneration is the ability to regenerate normal limb morphology and anatomical patterning. Although it is thought that regeneration uses similar mechanisms to those employed during development, it is not well understood how this is achieved in the context of varying blastema size. In a new study, Akira Satoh, Yoshihiro Morishita and colleagues investigate the allometric scaling of blastema size and pattern expressions of key genes relative to the size of the limb stump in axolotls. To find out more about the work, we caught up with first author Saya Furukawa, and corresponding authors Akira Satoh, professor at Okayama University, and Yoshihiro Morishita, Principal Investigator at RIKEN, Japan.

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来源期刊
Development
Development 生物-发育生物学
CiteScore
6.70
自引率
4.30%
发文量
433
审稿时长
3 months
期刊介绍: Development’s scope covers all aspects of plant and animal development, including stem cell biology and regeneration. The single most important criterion for acceptance in Development is scientific excellence. Research papers (articles and reports) should therefore pose and test a significant hypothesis or address a significant question, and should provide novel perspectives that advance our understanding of development. We also encourage submission of papers that use computational methods or mathematical models to obtain significant new insights into developmental biology topics. Manuscripts that are descriptive in nature will be considered only when they lay important groundwork for a field and/or provide novel resources for understanding developmental processes of broad interest to the community. Development includes a Techniques and Resources section for the publication of new methods, datasets, and other types of resources. Papers describing new techniques should include a proof-of-principle demonstration that the technique is valuable to the developmental biology community; they need not include in-depth follow-up analysis. The technique must be described in sufficient detail to be easily replicated by other investigators. Development will also consider protocol-type papers of exceptional interest to the community. We welcome submission of Resource papers, for example those reporting new databases, systems-level datasets, or genetic resources of major value to the developmental biology community. For all papers, the data or resource described must be made available to the community with minimal restrictions upon publication. To aid navigability, Development has dedicated sections of the journal to stem cells & regeneration and to human development. The criteria for acceptance into these sections is identical to those outlined above. Authors and editors are encouraged to nominate appropriate manuscripts for inclusion in one of these sections.
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