ANCA 阳性 EGPA 发病伴双侧胸腔积液：病例报告。

IF 2.4 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Current Medical Research and Opinion Pub Date : 2024-12-01 Epub Date: 2024-11-19 DOI:10.1080/03007995.2024.2427882

Alessandra Marchese, Rocco Accogli, Annalisa Frizzelli, Alessandro De Simoni, Olha Bondarenko, Roberta Pisi, Gaetano Caramori, Giovanna Pelà, Maria Majori, Letizia Gnetti, Agnese Aluia, Lorenzo D'Aloisio, Alfredo Chetta, Marina Aiello

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引用次数: 0

摘要

简介嗜酸性粒细胞肉芽肿伴多血管炎（EGPA）是一种多系统、免疫介导的疾病，多发于哮喘和嗜酸性粒细胞增多症患者。病例报告：在本报告中，我们介绍了一例不寻常的 EGPA 临床病例，患者的抗中性粒细胞胞浆抗体呈阳性，表现为双侧胸腔积液。诊断是通过实验室评估和支气管活检确诊的。结论：考虑到文献中记载的 EGPA 患者胸腔积液的证据有限，我们的病例显得非常有趣。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report.

Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small- and medium-caliber blood vessels.

Case report: This report presents an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms.

Conclusions: Our case appear interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature.

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来源期刊

Current Medical Research and Opinion 医学-医学：内科

CiteScore

4.40

自引率

4.30%

发文量

247

审稿时长

3-8 weeks

期刊介绍： Current Medical Research and Opinion is a MEDLINE-indexed, peer-reviewed, international journal for the rapid publication of original research on new and existing drugs and therapies, Phase II-IV studies, and post-marketing investigations. Equivalence, safety and efficacy/effectiveness studies are especially encouraged. Preclinical, Phase I, pharmacoeconomic, outcomes and quality of life studies may also be considered if there is clear clinical relevance