从 MiniMed™ 640G 转换到 770G 对连续血糖监测指标和 DTR-QOL 评分的影响:对日本 1 型糖尿病患者的观察研究。

IF 3.2 3区 医学
Toshiki Kogai, Junko Sato, Haruna Yasuda, Tatsuhiro Ayame, Azusa Ozaki, Eri Takagi, Mami Koshibu, Yuya Nishida, Fuki Ikeda, Hirotaka Watada
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引用次数: 0

摘要

目的/简介:我们评估了采用混合闭环技术的胰岛素泵 MiniMed™ 770G 对日本 1 型糖尿病患者血糖管理和生活质量的影响:这是一项为期 52 周的前瞻性观察研究。50 名日本 1 型糖尿病患者从 MiniMed™ 640G 换到了 770G,我们分析了在整个研究期间使用自动模式的 24 名受试者的连续血糖监测数据。我们还分析了 26 名自动模式用户在治疗改变前后完成的糖尿病治疗相关生活质量问卷的得分:结果:基线时间在 70-180 mg/dL 范围内的比例为 67.3 (54.8-78.4)%,从转换治疗模式 8 周后开始显著改善,并持续到 52 周。低于血糖范围的基线时间使用 MiniMed™ 770G 改善了连续血糖监测指标。然而,治疗满意度却有所下降,这可能是由于为维持自动模式而增加了血糖监测频率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of switching from MiniMed™ 640G to 770G on continuous glucose monitoring metrics and DTR-QOL scores: An observational study of Japanese people with type 1 diabetes mellitus.

Aims/introduction: We evaluated the effect of the MiniMed™ 770G, an insulin pump using hybrid closed-loop technology, on blood glucose management and quality of life in Japanese people with type 1 diabetes.

Materials and methods: This was a 52-week, prospective, observational study. Fifty Japanese people with type 1 diabetes switched from the MiniMed™ 640G to 770G, and we analyzed the continuous glucose monitoring data of 24 subjects who used auto mode throughout the study. We also analyzed the scores of the Diabetes Therapy-Related Quality of Life questionnaire completed by 26 auto-mode users before and after the treatment change.

Results: The baseline time in range 70-180 mg/dL was 67.3 (54.8-78.4)%, with a significant improvement beginning 8 weeks after the switch and lasting until 52 weeks. The baseline time below range <70 mg/dL was 1.9 (0.6-3.6)%, with a significant increase at week 8; however, the mean value was less than 4% throughout the study period. On the other hand, the number of blood glucose measurements significantly increased. While there was no significant difference in the overall change in the total Diabetes Therapy-Related Quality of Life score, there was a significant decrease in the treatment satisfaction score.

Conclusions: Use of the MiniMed™ 770G improved continuous glucose monitoring metrics. However, treatment satisfaction decreased, probably due to the increased frequency of blood glucose monitoring necessary to maintain auto mode.

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来源期刊
Journal of Diabetes Investigation
Journal of Diabetes Investigation Medicine-Internal Medicine
自引率
9.40%
发文量
218
期刊介绍: Journal of Diabetes Investigation is your core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes (AASD). The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. Embracing clinical and experimental research in diabetes and related areas, the Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology. Translational research focused on the exchange of ideas between clinicians and researchers is also welcome. Journal of Diabetes Investigation is indexed by Science Citation Index Expanded (SCIE).
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