医药创新：进化经济学如何塑造医药研发的未来。

IF 6.5 2区医学 Q1 PHARMACOLOGY & PHARMACY

Drug Discovery Today Pub Date : 2024-11-05 DOI:10.1016/j.drudis.2024.104222

Alexander Schuhmacher

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引用次数: 0

摘要

本文介绍了医药研发背景下的演化经济学理论。在此背景下，研发生产率危机是一个关键的选择机制，而研发、技术和行业趋势则提供了变异机制。借鉴当今领先制药公司的主流商业模式--生物技术杠杆制药公司（BIPCO），我提出了两种新的价值创造逻辑：技术研究型制药公司（TIPCO）和资产整合型制药公司（AIPCO）。虽然有些公司已经拥有这些商业模式的某些方面，但从进化经济学的角度来看，制药研发进化过程的最终结果如何尚不清楚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pharma innovation: how evolutionary economics is shaping the future of pharma R&D.

This paper describes the theory of evolutionary economics in the context of pharmaceutical R&D. In this context, the R&D productivity crisis acts as a key selection mechanism, and R&D, technology and industry trends provide mechanisms of variation. Drawing on today's prevailing business model among leading pharmaceutical companies, the biotech-leveraged pharma company (BIPCO), I propose two new value creation logics: the technology-investigating pharma company (TIPCO) and the asset-integrating pharma company (AIPCO). Although some companies already share aspects of these business models, it is not yet clear, in terms of evolutionary economics, what the ultimate outcome of the evolutionary process in pharma R&D will be.

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来源期刊

Drug Discovery Today 医学-药学

CiteScore

14.80

自引率

2.70%

发文量

293

审稿时长

6 months

期刊介绍： Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.