面向多巴胺应用的多巴胺分子结构改造

IF 2.5 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2024-11-07 DOI:10.1002/ejoc.202401035

Yoonji Heo, Minseo Ji, Chae Young Ryu, Haein Kim, Isaac Choi, Sung Min Kang, Min Kim

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引用次数: 0

摘要

聚多巴胺（PDA）是通过多巴胺在碱性条件下的氧化自聚合反应合成的一种合成材料。这种材料仿效了贻贝足蛋白的粘合特性，可在各种表面形成坚固稳定的有机涂层。研究人员试图通过加入更多的有机官能团来确定和改进 PDA 的表面涂层特性。本综述探讨了多巴胺分子在有机化学层面的结构修饰，重点是儿茶酚分子和脂肪胺的变化，并研究了它们对 PDA 应用的影响。这些改性的灵活性凸显了它们对于优化 PDA 涂层的重要性，使其能广泛应用于各种领域。

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Structural Modifications on Dopamine Molecules toward Polydopamine Applications

Polydopamine (PDA) is a synthetic material synthesized through the oxidative self‐polymerization of dopamine under alkaline conditions. This material emulates the adhesive properties of mussel foot proteins, allowing the formation of robust and stable organic coatings on various surfaces. Researchers have attempted to identify and improve the surface‐coating properties of PDA by incorporating additional organic functional groups. This review explores the structural modifications of dopamine molecules at the organic chemistry level, with a focus on changes in the catechol moiety and aliphatic amines, and examines their impact on the applications of PDA. The flexibility of these modifications underscores their importance for optimizing PDA coatings for a wide range of applications.

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.