Qiuping Tang, Yuanfang Wang, Yu Yuan, Ling Shu, Jin Deng, Chao He
{"title":"[2019-2023年从6428名肿瘤患者中分离出的病原体分布及相关耐药性监测报告】。］","authors":"Qiuping Tang, Yuanfang Wang, Yu Yuan, Ling Shu, Jin Deng, Chao He","doi":"10.12182/20240960602","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the characteristics of the pathogens isolated from the specimens of tumor patients and detection rates of multidrug-resistant bacteria in a hospital in the past five years, so as to provide references for infection prevention and control.</p><p><strong>Methods: </strong>The results of pathogenic culture and <i>in vitro</i> susceptibility of the strains isolated from the specimens collected between January 2019 and December 2023 from tumor patients were retrospectively collected, and the trends of the data were analyzed and summarized.</p><p><strong>Results: </strong>A total of 16393 strains were isolated from 80386 specimens, producing a detection rate of 20.4%. After excluding the duplicate strains isolated from the same patients, <i>Escherichia coli</i> (14.5%), <i>Klebsiella pneumoniae</i> (13.2%), <i>Staphylococcus aureus</i> (9.4%), <i>Acinetobacter baumannii</i> complex (9.3%), and <i>Pseudomonas aeruginosa</i> (7.7%) predominated the 7951 (81.1%) bacterial strains. Among the 1857 (18.9%) fungal strains, <i>Candida albicans</i> (56.5%), <i>Candida tropicalis</i> (9.0%), and <i>Candida parapsilosis</i> (8.0%) were the most common ones. The specimen sources differed among the prevalent species, and the species distribution varied among specimens from different types of tumors (<i>P</i><0.05). The detection rates of carbapenem-resistant <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> were 2.5% (29/1152) and 12.3% (129/1050), respectively. The detection rate of methicillin-resistant <i>Staphylococcus aureus</i> was 22.0% (165/749), maintaining an upward trend in the last four years (<i>P</i><0.01). The detection rates of carbapenem-resistant <i>Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i> were 40.3% (298/739) and 8.8% (54/612), respectively.</p><p><strong>Conclusion: </strong>Gram-negative bacteria were the prevalent pathogens of tumor patients. The detection rate of multidrug-resistant bacteria was relatively high, and the detection rate of methicillin-resistant <i>Staphylococcus aureus</i> showed an upward trend.</p>","PeriodicalId":39321,"journal":{"name":"四川大学学报(医学版)","volume":"55 5","pages":"1264-1271"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536249/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Distribution of the Pathogens Isolated from 6428 Tumor Patients in 2019-2023 and the Relevant Drug Resistance Surveillance Report].\",\"authors\":\"Qiuping Tang, Yuanfang Wang, Yu Yuan, Ling Shu, Jin Deng, Chao He\",\"doi\":\"10.12182/20240960602\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To investigate the characteristics of the pathogens isolated from the specimens of tumor patients and detection rates of multidrug-resistant bacteria in a hospital in the past five years, so as to provide references for infection prevention and control.</p><p><strong>Methods: </strong>The results of pathogenic culture and <i>in vitro</i> susceptibility of the strains isolated from the specimens collected between January 2019 and December 2023 from tumor patients were retrospectively collected, and the trends of the data were analyzed and summarized.</p><p><strong>Results: </strong>A total of 16393 strains were isolated from 80386 specimens, producing a detection rate of 20.4%. After excluding the duplicate strains isolated from the same patients, <i>Escherichia coli</i> (14.5%), <i>Klebsiella pneumoniae</i> (13.2%), <i>Staphylococcus aureus</i> (9.4%), <i>Acinetobacter baumannii</i> complex (9.3%), and <i>Pseudomonas aeruginosa</i> (7.7%) predominated the 7951 (81.1%) bacterial strains. Among the 1857 (18.9%) fungal strains, <i>Candida albicans</i> (56.5%), <i>Candida tropicalis</i> (9.0%), and <i>Candida parapsilosis</i> (8.0%) were the most common ones. The specimen sources differed among the prevalent species, and the species distribution varied among specimens from different types of tumors (<i>P</i><0.05). The detection rates of carbapenem-resistant <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> were 2.5% (29/1152) and 12.3% (129/1050), respectively. The detection rate of methicillin-resistant <i>Staphylococcus aureus</i> was 22.0% (165/749), maintaining an upward trend in the last four years (<i>P</i><0.01). The detection rates of carbapenem-resistant <i>Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i> were 40.3% (298/739) and 8.8% (54/612), respectively.</p><p><strong>Conclusion: </strong>Gram-negative bacteria were the prevalent pathogens of tumor patients. The detection rate of multidrug-resistant bacteria was relatively high, and the detection rate of methicillin-resistant <i>Staphylococcus aureus</i> showed an upward trend.</p>\",\"PeriodicalId\":39321,\"journal\":{\"name\":\"四川大学学报(医学版)\",\"volume\":\"55 5\",\"pages\":\"1264-1271\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536249/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"四川大学学报(医学版)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12182/20240960602\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"四川大学学报(医学版)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12182/20240960602","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Distribution of the Pathogens Isolated from 6428 Tumor Patients in 2019-2023 and the Relevant Drug Resistance Surveillance Report].
Objective: To investigate the characteristics of the pathogens isolated from the specimens of tumor patients and detection rates of multidrug-resistant bacteria in a hospital in the past five years, so as to provide references for infection prevention and control.
Methods: The results of pathogenic culture and in vitro susceptibility of the strains isolated from the specimens collected between January 2019 and December 2023 from tumor patients were retrospectively collected, and the trends of the data were analyzed and summarized.
Results: A total of 16393 strains were isolated from 80386 specimens, producing a detection rate of 20.4%. After excluding the duplicate strains isolated from the same patients, Escherichia coli (14.5%), Klebsiella pneumoniae (13.2%), Staphylococcus aureus (9.4%), Acinetobacter baumannii complex (9.3%), and Pseudomonas aeruginosa (7.7%) predominated the 7951 (81.1%) bacterial strains. Among the 1857 (18.9%) fungal strains, Candida albicans (56.5%), Candida tropicalis (9.0%), and Candida parapsilosis (8.0%) were the most common ones. The specimen sources differed among the prevalent species, and the species distribution varied among specimens from different types of tumors (P<0.05). The detection rates of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae were 2.5% (29/1152) and 12.3% (129/1050), respectively. The detection rate of methicillin-resistant Staphylococcus aureus was 22.0% (165/749), maintaining an upward trend in the last four years (P<0.01). The detection rates of carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa were 40.3% (298/739) and 8.8% (54/612), respectively.
Conclusion: Gram-negative bacteria were the prevalent pathogens of tumor patients. The detection rate of multidrug-resistant bacteria was relatively high, and the detection rate of methicillin-resistant Staphylococcus aureus showed an upward trend.
四川大学学报(医学版)Biochemistry, Genetics and Molecular Biology-Molecular Biology
CiteScore
0.70
自引率
0.00%
发文量
8695
期刊介绍：
"Journal of Sichuan University (Medical Edition)" is a comprehensive medical academic journal sponsored by Sichuan University, a higher education institution directly under the Ministry of Education of the People's Republic of China. It was founded in 1959 and was originally named "Journal of Sichuan Medical College". In 1986, it was renamed "Journal of West China University of Medical Sciences". In 2003, it was renamed "Journal of Sichuan University (Medical Edition)" (bimonthly).
"Journal of Sichuan University (Medical Edition)" is a Chinese core journal and a Chinese authoritative academic journal (RCCSE). It is included in the retrieval systems such as China Science and Technology Papers and Citation Database (CSTPCD), China Science Citation Database (CSCD) (core version), Peking University Library's "Overview of Chinese Core Journals", the U.S. "Index Medica" (IM/Medline), the U.S. "PubMed Central" (PMC), the U.S. "Biological Abstracts" (BA), the U.S. "Chemical Abstracts" (CA), the U.S. EBSCO, the Netherlands "Abstracts and Citation Database" (Scopus), the Japan Science and Technology Agency Database (JST), the Russian "Abstract Magazine", the Chinese Biomedical Literature CD-ROM Database (CBMdisc), the Chinese Biomedical Periodical Literature Database (CMCC), the China Academic Journal Network Full-text Database (CNKI), the Chinese Academic Journal (CD-ROM Edition), and the Wanfang Data-Digital Journal Group.
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