Muhammad Faisal Afridi, Junaid Ahmed Khan, Ahmed Fatimi, Farooq Nazir, Usman Javed, Khurrum Shehzad Quraishi
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引用次数: 0
摘要
在过去的二十年里,壳聚糖纳米颗粒(CSNPs)在癌症治疗中的药物输送应用有了大幅增长。然而,对这一新兴领域缺乏全面的文献计量分析。本次分析对 2000 年至 2022 年用于癌症靶向给药的 CSNPs 的研究演变和趋势进行了详细的文献计量学评估。我们使用 VOSviewer、Bibliometrix 和 MS Excel 对科学网核心数据库(WoSCC)中的 626 篇出版物进行了评估。我们进行了深入探讨,以发现该特定研究领域的出版趋势、最有成果的作者、所属单位、国家和期刊以及高被引论文。Ick Chan Kwon 是在这一领域做出重大贡献的最杰出的作者。在用于癌症靶向给药的 CSNPs 研究方面,中国居于领先地位,其次是印度和伊朗。在论文总数方面,《国际生物大分子学报》(The International Journal of Biological Macromolecules)在该研究领域居于领先地位。此外,通过分析作者最常用的关键词,我们还发现了研究趋势和热点。我们的分析凸显了 CSNPs 在癌症药物递送方面日益增长的研究兴趣,强调了进一步探索以充分释放其潜力的必要性。
Exploring the Impact of Chitosan-Based Nanoparticles in Cancer Targeted Drug Delivery: A Bibliometric Review.
Over the last two decades, there has been a considerable increase in the usage of chitosan nanoparticles (CSNPs) for drug delivery applications in cancer treatment. However, a comprehensive bibliometric analysis of this emerging field is lacking. The current analysis pre-sents a detailed bibliometric assessment of the research evolution and trends in CSNPs for can-cer targeted-drug delivery from 2000 to 2022. A total of 626 publications from the Web of Science Core Collection (WoSCC) database were evaluated using VOSviewer, Bibliometrix, and MS Excel. An in-depth exploration was carried out to find publication trends, the most productive authors, affiliations, countries, and journals as well as the highly cited publications within this particular research domain. Ick Chan Kwon was the most prominent author who made significant contributions to this field. China was the leading country in terms of research on CSNPs for cancer-targeted drug delivery, followed by India and Iran. Concerning the total number of publications, The International Journal of Biological Macromolecules excelled as the leading journal in this research area. Furthermore, the research trends and hotspots were also identified through the analysis of the most commonly used keywords by the authors. Our analysis highlights the growing research interest in CSNPs for cancer drug delivery, emphasiz-ing the need for further exploration to unlock their full potential.
期刊介绍:
Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes.
Current Cancer Drug Targets publishes original research articles, letters, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.