CatLet 评分系统对慢性冠状动脉综合征患者经皮冠状动脉介入治疗后长期预后的预测价值。

IF 2.1 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Juan Wang, Mingchao Zhang, Mingxing Xu, Jiayan Zhou, Dasheng Lu
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引用次数: 0

摘要

背景:冠状动脉树描述和病变评估(CatLet)血管造影评分系统是一种新开发的血管评分系统,用于评估冠状动脉狭窄程度和冠状动脉变异性。初步研究表明,在预测急性心肌梗死(AMI)患者的预后方面,该系统优于 Taxus 和心脏手术经皮冠状动脉介入治疗(PCI)协同评分系统(SYNTAX)。本研究旨在评估CatLet评分对慢性冠状动脉综合征(CCS)PCI术后长期预后的预测价值:2020年1月至2021年6月,在中国皖南医学院第二附属医院接受冠状动脉DES植入术并可计算Catlet评分的201例慢性冠脉综合征患者连续入组。主要终点为主要心脏不良事件(MACEs),定义为心肌梗死、复发性心绞痛、心源性死亡、心力衰竭和缺血驱动的血管再通的复合事件,根据CatLet评分分层:0≤CatLet_low≤23(n = 66)、CatLet_mid 24-43(n = 68)和CatLet_top≥44(n = 67):CatLet评分可预测长期预后,中位随访时间为3.0年。在分析的 201 例患者中,MACE 和心源性死亡的发生率分别为 25.37% 和 3.98%。所有终点的 Kaplan-Meier 曲线均显示,随着 CatLet 评分 tertiles 的增加,结果事件也随之增加,P 值为 结论:CatLet 评分是经皮冠状动脉介入治疗后慢性冠状动脉综合征患者长期临床结局的独立预测指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Predictive Value of the CatLet Scoring System for Long-Term Prognosis After Percutaneous Coronary Intervention in Patients With Chronic Coronary Syndrome.

Background: Coronary Artery Tree description and Lesion EvaluaTion (CatLet) angiographic scoring system is a newly developed vascular scoring for assessing the degree of coronary artery stenosis and coronary artery variability. Preliminary studies have demonstrated its superiority over the Synergy between percutaneous coronary intervention (PCI) with Taxus and Cardiac Surgery (SYNTAX) score in predicting outcome in patients with acute myocardial infarction (AMI). This study aimed to assess the predictive value of the CatLet score in long-term prognosis after PCI for chronic coronary syndrome (CCS).

Methods: A total of 201 patients, who were diagnosed with chronic coronary syndrome, undergoing coronary DES implantation and calculable Catlet score at the Second Affiliated Hospital of Wannan Medical College in China were consecutively enrolled from January 2020 to June 2021. The primary endpoint was major adverse cardiac events (MACEs), defined as a composite of myocardial infarction, recurrent angina, cardiac death, heart failure and ischemia-driven revascularization, were stratified according to CatLet score tertiles: 0 ≤ CatLet_low ≤ 23(n = 66), CatLet_mid 24-43(n = 68), and CatLet_top ≥ 44(n = 67), respectively.

Results: The CatLet score predicted long-term prognosis with a median follow-up of 3.0 years. Of 201 patients analyzed, the rates of MACEs and cardiac death were 25.37% and 3.98%, respectively. The Kaplan-Meier curves for all endpoints showed increasing outcome events with the increasing tertiles of the CatLet score, with p-value < 0.05 on the trend test. For MACE and cardiac death, the area under the curve (AUC) of the CatLet score was 0.744 (95% confidence interval [CI]: 0.668-0.820) and 0.804 (95% CI: 0.672-0.936), respectively; Alone or after adjusting for risk factors, the multivariable-adjusted hazard ratio (95% CI)/unit higher score was 9.41 (3.18-27.85) for MACEs and 1.85 (1.20-2.84) for cardiac death, respectively.

Conclusion: The CatLet score is an independent predictor of long-term clinical outcomes in patients with chronic coronary syndrome after percutaneous coronary intervention.

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来源期刊
CiteScore
5.40
自引率
8.70%
发文量
419
审稿时长
2 months
期刊介绍: Catheterization and Cardiovascular Interventions is an international journal covering the broad field of cardiovascular diseases. Subject material includes basic and clinical information that is derived from or related to invasive and interventional coronary or peripheral vascular techniques. The journal focuses on material that will be of immediate practical value to physicians providing patient care in the clinical laboratory setting. To accomplish this, the journal publishes Preliminary Reports and Work In Progress articles that complement the traditional Original Studies, Case Reports, and Comprehensive Reviews. Perspective and insight concerning controversial subjects and evolving technologies are provided regularly through Editorial Commentaries furnished by members of the Editorial Board and other experts. Articles are subject to double-blind peer review and complete editorial evaluation prior to any decision regarding acceptability.
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