医院获得性静脉血栓栓塞症的发病率和风险因素。

Hai-Lei Li, He Zhang, Yiu Che Chan, Stephen W Cheng
{"title":"医院获得性静脉血栓栓塞症的发病率和风险因素。","authors":"Hai-Lei Li, He Zhang, Yiu Che Chan, Stephen W Cheng","doi":"10.1177/02683555241297566","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the prevalence, clinical characteristics and risk factors of hospital acquired venous thromboembolism (HA-VTE) in a Chinese Hospital.</p><p><strong>Methods: </strong>Retrospective analysis of patients diagnosed as HA-VTE in a single institution from January 2016 to December 2022 was performed. Patients with VTE prior to admission or within 48 h after admission were excluded. Demographic data of patients was retrieved from the electronic medical database, and parameters affecting the occurrence of HA-VTE were analyzed.</p><p><strong>Results: </strong>4,022 patients from 321,997 episodes of medical admissions were diagnosed as VTE. Among these, 952 (23.7%) fulfilled the criteria of HA-VTE, corresponding to an incidence of 0.296%. 76% of patients presented with HA-deep vein thrombosis (DVT) alone, 13% presented with isolated HA-pulmonary embolism (PE), and 11% presented with concomitant HA- DVT and PE. Risk factor analyses showed statistically higher incidence in patients with elder age (67.5 ± 15.5 vs 48.3 ± 17.2 years, <i>p</i> < .001), male gender (0.346% vs 0.262%, <i>p</i> < .001), malignancy (0.513% vs 0.252%, <i>p</i> < .001), trauma (0.659% vs 0.28%, <i>p</i> < .001), emergency admission (0.664% vs 0.186%, <i>p</i> < .001), ICU stay (2.981% vs 0.226%, <i>p</i> < .001), and patients undergoing major surgery (0.702% vs 0.176%, <i>p</i> < .001). Patients with HA-VTE had longer hospital stay (22.5 ± 26.6 vs 7.21 ± 9.23 days, <i>p</i> < .001) and higher mortality rate (8.51% vs 1.01%, <i>p</i> < .001). The crude incidence rate of HA-VTE increased annually from 0.75 per 1,000 patients in 2016 to 5.89 per 1,000 patients in 2022. The subspecialties with the highest incidence rate of HA-VTE were cardiovascular surgery (1.40%), neurosurgery (1.10%), and respiratory medicine (0.72%).</p><p><strong>Conclusion: </strong>This is one of the few large scale studies to show that HA-VTE, accounting for nearly one quarter of all VTE events, occurs in 0.296% of adult hospitalizations. Patients with elder age, malignancy, ICU stay, and undergoing major surgery require more intensive HA-VTE surveillance and prevention.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555241297566"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence and risk factors of hospital acquired venous thromboembolism.\",\"authors\":\"Hai-Lei Li, He Zhang, Yiu Che Chan, Stephen W Cheng\",\"doi\":\"10.1177/02683555241297566\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To investigate the prevalence, clinical characteristics and risk factors of hospital acquired venous thromboembolism (HA-VTE) in a Chinese Hospital.</p><p><strong>Methods: </strong>Retrospective analysis of patients diagnosed as HA-VTE in a single institution from January 2016 to December 2022 was performed. Patients with VTE prior to admission or within 48 h after admission were excluded. Demographic data of patients was retrieved from the electronic medical database, and parameters affecting the occurrence of HA-VTE were analyzed.</p><p><strong>Results: </strong>4,022 patients from 321,997 episodes of medical admissions were diagnosed as VTE. Among these, 952 (23.7%) fulfilled the criteria of HA-VTE, corresponding to an incidence of 0.296%. 76% of patients presented with HA-deep vein thrombosis (DVT) alone, 13% presented with isolated HA-pulmonary embolism (PE), and 11% presented with concomitant HA- DVT and PE. Risk factor analyses showed statistically higher incidence in patients with elder age (67.5 ± 15.5 vs 48.3 ± 17.2 years, <i>p</i> < .001), male gender (0.346% vs 0.262%, <i>p</i> < .001), malignancy (0.513% vs 0.252%, <i>p</i> < .001), trauma (0.659% vs 0.28%, <i>p</i> < .001), emergency admission (0.664% vs 0.186%, <i>p</i> < .001), ICU stay (2.981% vs 0.226%, <i>p</i> < .001), and patients undergoing major surgery (0.702% vs 0.176%, <i>p</i> < .001). Patients with HA-VTE had longer hospital stay (22.5 ± 26.6 vs 7.21 ± 9.23 days, <i>p</i> < .001) and higher mortality rate (8.51% vs 1.01%, <i>p</i> < .001). The crude incidence rate of HA-VTE increased annually from 0.75 per 1,000 patients in 2016 to 5.89 per 1,000 patients in 2022. The subspecialties with the highest incidence rate of HA-VTE were cardiovascular surgery (1.40%), neurosurgery (1.10%), and respiratory medicine (0.72%).</p><p><strong>Conclusion: </strong>This is one of the few large scale studies to show that HA-VTE, accounting for nearly one quarter of all VTE events, occurs in 0.296% of adult hospitalizations. Patients with elder age, malignancy, ICU stay, and undergoing major surgery require more intensive HA-VTE surveillance and prevention.</p>\",\"PeriodicalId\":94350,\"journal\":{\"name\":\"Phlebology\",\"volume\":\" \",\"pages\":\"2683555241297566\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phlebology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/02683555241297566\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phlebology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/02683555241297566","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的调查一家中国医院医院获得性静脉血栓栓塞症(HA-VTE)的发病率、临床特征和风险因素:方法:对2016年1月至2022年12月在一家医院确诊为HA-VTE的患者进行回顾性分析。排除入院前或入院后48小时内发生VTE的患者。从电子医疗数据库中检索了患者的人口统计学数据,并分析了影响HA-VTE发生的参数:结果:在 321,997 次入院治疗中,有 4,022 名患者被诊断为 VTE。其中,952 人(23.7%)符合 HA-VTE 标准,发病率为 0.296%。76%的患者仅表现为HA-深静脉血栓形成(DVT),13%的患者表现为孤立的HA-肺栓塞(PE),11%的患者同时表现为HA-深静脉血栓形成和PE。风险因素分析显示,年龄较大(67.5 ± 15.5 岁 vs 48.3 ± 17.2 岁,P < .001)、性别为男性(0.346% vs 0.262%,P < .001)、恶性肿瘤(0.513% vs 0.252%,p < .001)、外伤(0.659% vs 0.28%,p < .001)、急诊入院(0.664% vs 0.186%,p < .001)、重症监护室住院(2.981% vs 0.226%,p < .001)以及接受大手术的患者(0.702% vs 0.176%,p < .001)。HA-VTE 患者的住院时间更长(22.5 ± 26.6 天 vs 7.21 ± 9.23 天,P < .001),死亡率更高(8.51% vs 1.01%,P < .001)。HA-VTE的粗发病率从2016年的每千名患者0.75例逐年上升至2022年的每千名患者5.89例。HA-VTE 发生率最高的亚专科是心血管外科(1.40%)、神经外科(1.10%)和呼吸内科(0.72%):这是为数不多的大规模研究之一,研究显示 HA-VTE 占所有 VTE 事件的近四分之一,在成人住院患者中的发生率为 0.296%。高龄、恶性肿瘤、入住重症监护室和接受大手术的患者需要加强 HA-VTE 监测和预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and risk factors of hospital acquired venous thromboembolism.

Objectives: To investigate the prevalence, clinical characteristics and risk factors of hospital acquired venous thromboembolism (HA-VTE) in a Chinese Hospital.

Methods: Retrospective analysis of patients diagnosed as HA-VTE in a single institution from January 2016 to December 2022 was performed. Patients with VTE prior to admission or within 48 h after admission were excluded. Demographic data of patients was retrieved from the electronic medical database, and parameters affecting the occurrence of HA-VTE were analyzed.

Results: 4,022 patients from 321,997 episodes of medical admissions were diagnosed as VTE. Among these, 952 (23.7%) fulfilled the criteria of HA-VTE, corresponding to an incidence of 0.296%. 76% of patients presented with HA-deep vein thrombosis (DVT) alone, 13% presented with isolated HA-pulmonary embolism (PE), and 11% presented with concomitant HA- DVT and PE. Risk factor analyses showed statistically higher incidence in patients with elder age (67.5 ± 15.5 vs 48.3 ± 17.2 years, p < .001), male gender (0.346% vs 0.262%, p < .001), malignancy (0.513% vs 0.252%, p < .001), trauma (0.659% vs 0.28%, p < .001), emergency admission (0.664% vs 0.186%, p < .001), ICU stay (2.981% vs 0.226%, p < .001), and patients undergoing major surgery (0.702% vs 0.176%, p < .001). Patients with HA-VTE had longer hospital stay (22.5 ± 26.6 vs 7.21 ± 9.23 days, p < .001) and higher mortality rate (8.51% vs 1.01%, p < .001). The crude incidence rate of HA-VTE increased annually from 0.75 per 1,000 patients in 2016 to 5.89 per 1,000 patients in 2022. The subspecialties with the highest incidence rate of HA-VTE were cardiovascular surgery (1.40%), neurosurgery (1.10%), and respiratory medicine (0.72%).

Conclusion: This is one of the few large scale studies to show that HA-VTE, accounting for nearly one quarter of all VTE events, occurs in 0.296% of adult hospitalizations. Patients with elder age, malignancy, ICU stay, and undergoing major surgery require more intensive HA-VTE surveillance and prevention.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信