模仿肺癌的肺梅里埃病：诊断难题。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-11-06 DOI:10.1093/trstmh/trae089

Xiaohong Yang, Zhuopeng Ying, Yuefu Zhan, Jianqiang Chen

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引用次数: 0

摘要

背景：肺梅里埃病和肺癌的临床和影像学特征相互重叠，这给医疗服务提供者的诊断带来了挑战：肺黄疽和肺癌的临床和影像学特征相互重叠，这给地方病流行地区的医疗服务提供者带来了诊断上的挑战：我们比较了19例肺部黄疽病例与15例小细胞肺癌（SCLC）和17例非小细胞肺癌（NSCLC）病例的临床、实验室和影像学特征：结果：与小细胞肺癌/非小细胞肺癌病例相比，肺肉芽肿病病例在发病时更可能患有糖尿病、发热、中性粒细胞增多症和白细胞增多症（p结论：尽管肺肉芽肿病与小细胞肺癌/非小细胞肺癌病例的表现相似，但肺肉芽肿病病例在发病时更可能患有糖尿病、发热、中性粒细胞增多症和白细胞增多症：尽管肺肉芽肿病、SCLC 和 NSCLC 在表现形式上有相似之处，但一些临床、实验室和影像学因素可能有助于区分这些诊断并改善患者护理。

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Pulmonary melioidosis mimicking lung cancer: a diagnostic challenge.

Background: The overlapping clinical and radiographic features of pulmonary melioidosis and lung cancer present diagnostic challenges to healthcare providers in endemic settings.

Methods: We compared the clinical, laboratory and imaging characteristics of 19 pulmonary melioidosis cases with those of 15 cases of small cell lung cancer (SCLC) and 17 cases of non-small cell lung cancer (NSCLC).

Results: Compared with SCLC/NSCLC cases, those with pulmonary melioidosis were more likely to have diabetes, have fever, neutrophilia and leukocytosis on presentation (p<0.05). While certain CT imaging features were shared between pulmonary melioidosis and SCLC ('frozen mediastinum sign', 'vascular encasement sign'), extensive liquefactive necrosis, uneven ring-enhancement, circular lesions and 'air-bubble' signs were more commonly seen in pulmonary melioidosis cases than in those with SCLC/NSCLC (p<0.05).

Conclusions: Despite the similarities in presentation of pulmonary melioidosis, SCLC and NSCLC, several clinical, laboratory and imaging factors may help delineate these diagnoses and improve patient care.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.