Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie
{"title":"克里特岛夏尼亚和伊拉克利翁金黄色葡萄球菌分离菌株的克隆分布和分子特征。","authors":"Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie","doi":"10.15386/mpr-2783","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of <i>Staphylococcus aureus</i> infections.</p><p><strong>Methods: </strong>The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.</p><p><strong>Results: </strong>The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were <i>MRSA</i>, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were <i>Pvl</i>-positive, highlighting the presence of both <i>MRSA</i> and <i>MSSA</i> strains with <i>Pvl</i> genes.</p><p><strong>Conclusions: </strong>The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of <i>MRSA</i>, particularly in vulnerable populations.</p>","PeriodicalId":18438,"journal":{"name":"Medicine and Pharmacy Reports","volume":"97 4","pages":"456-466"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534380/pdf/","citationCount":"0","resultStr":"{\"title\":\"Clonal distribution and molecular characterization of <i>Staphylococcus aureus</i> isolated strains in Chania and Heraklion, Crete.\",\"authors\":\"Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie\",\"doi\":\"10.15386/mpr-2783\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of <i>Staphylococcus aureus</i> infections.</p><p><strong>Methods: </strong>The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.</p><p><strong>Results: </strong>The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were <i>MRSA</i>, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were <i>Pvl</i>-positive, highlighting the presence of both <i>MRSA</i> and <i>MSSA</i> strains with <i>Pvl</i> genes.</p><p><strong>Conclusions: </strong>The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of <i>MRSA</i>, particularly in vulnerable populations.</p>\",\"PeriodicalId\":18438,\"journal\":{\"name\":\"Medicine and Pharmacy Reports\",\"volume\":\"97 4\",\"pages\":\"456-466\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534380/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine and Pharmacy Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15386/mpr-2783\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine and Pharmacy Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15386/mpr-2783","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Clonal distribution and molecular characterization of Staphylococcus aureus isolated strains in Chania and Heraklion, Crete.
Aim: This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of Staphylococcus aureus infections.
Methods: The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.
Results: The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were MRSA, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were Pvl-positive, highlighting the presence of both MRSA and MSSA strains with Pvl genes.
Conclusions: The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of MRSA, particularly in vulnerable populations.
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