评估禽再障病毒变种在产蛋母鸡中的感染性、感染时间和免疫反应。

IF 2.5 2区农林科学 Q1 VETERINARY SCIENCES

Avian Pathology Pub Date : 2024-12-17 DOI:10.1080/03079457.2024.2425353

Yi Tang, Haiyang Yu, Muhammad Zubair Shabbir, Carrington Stephenson, Patrica A Dunn, Eva A Wallner-Pendleton, Huaguang Lu

引用次数: 0

摘要

ABSTRACT 我们对蛋鸡的禽再病毒（ARV）感染性进行了研究，重点是迄今为止在宾夕法尼亚州蛋鸡中发现的三种变种（δC 基因型 2、3 和 5）。在宾夕法尼亚州立大学帕克校区家禽教育与研究中心饲养的鸡苗（Hy-Line North America, LLC, PA）在 20 周龄后表现出健康的生长和正常的产蛋量。ARV 变异株在 LMH 细胞培养物中繁殖，浓度按 TCID50/mL 测定。每组 10 只母鸡通过口腔、鼻腔和眼部途径接受 1.0 mL 剂量（含 103-104 TCID50/mL 的一种 ARV 变种）。受感染的母鸡产蛋正常，在接种后第一周（π）粪便呈水样的症状极少。在接种后的第一周，每天采集泄殖腔和口腔咽拭子，第二周隔天采集一次，以监测病毒脱落情况。病毒从 24 小时后开始通过粪便脱落，2 到 4 天后达到高峰，5 到 7 天后开始减少，12 到 14 天后停止。少数鸡的口腔咽拭子在感染后 1 到 3 天内呈弱阳性，随后全部转为阴性。受感染的母鸡在发病前 2 至 3 周出现高血清抗体和卵黄抗体滴度，对随后感染相同变异株的鸡有 100%的保护作用，显示出 100%的保护率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Evaluation of infectivity, length of infection, and immune response of avian reovirus variants in egg-laying hens.

Research highlights: Avian reovirus-infected hens shed virus heavily at 2-3 days post-inoculation.Shedding became minimal after 5-7 days post-inoculation.ARV variants offered 100% protection in hens upon subsequent infections.Infected hens maintained normal egg production with no observable clinical signs.

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来源期刊

Avian Pathology 农林科学-兽医学

CiteScore

4.50

自引率

10.70%

发文量

审稿时长

1 months

期刊介绍： Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.