使用 68Ga-Trivehexin 进行癌症特异性整合素成像：甲状腺恶性肿瘤准确分期的潜在成像技术

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-11-05 DOI:10.1097/RLU.0000000000005557

Tejasvini Singhal, Kanhaiyalal Agrawal, Srijani Mandal, Girish Kumar Parida

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引用次数: 0

摘要

摘要：68Ga-Trivehexin是一种与 "癌症特异性整合素αvβ6 "结合的新型放射性示踪剂。68Ga-Trivehexin对肿瘤细胞具有高度特异性，因此有可能取代18F-FDG PET/CT在头颈部癌症中有限的特异性。在这里，我们介绍了一例甲状腺乳头状癌病例，与 18F-FDG PET/CT 相比，68Ga-Trivehexin PET CT 显示了准确的分期。

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Cancer-Specific Integrin Imaging With 68 Ga-Trivehexin : A Potential Imaging for Accurate Staging of Thyroid Malignancy.

Abstract: 68 Ga-Trivehexin is a novel radiotracer binding to "cancer-specific integrin αvβ6." 68 Ga-Trivehexin has high specificity for tumor cells and, thus, has the potential to replace 18 F-FDG PET/CT due to its limited specificity in the head and neck cancer. Here, we present one case of papillary thyroid carcinoma, where 68 Ga-Trivehexin PET CT demonstrated accurate staging compared with 18 F-FDG PET/CT.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.