癌症恶病质靶向疗法即将问世--我们能为患者带来哪些临床益处？

IF 3.1 2区化学 Q2 CHEMISTRY, ANALYTICAL

Journal of Analytical Atomic Spectrometry Pub Date : 2024-11-05 DOI:10.1038/s41571-024-00964-1

Vickie E. Baracos

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引用次数: 0

摘要

一些针对下丘脑和脑干中控制食欲、摄食行为、饱腹感、恶心和呕吐的信号介质的疗法正开始推动癌症恶病质的治疗。然而，还需要明确对患者有意义的临床益处以及支持恶病质治疗获得监管部门批准的主要终点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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On the cusp of targeted therapy for cancer cachexia — what clinical benefits might we promise our patients?

A number of therapeutics that target mediators of signalling in the hypothalamic and brainstem regions that control appetite, ingestive behaviour, satiety, nausea and vomiting are starting to move the needle on cancer cachexia. However, clarification of meaningful clinical benefits for patients and the primary end points that should support regulatory approval of cachexia treatments is needed.

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来源期刊

Journal of Analytical Atomic Spectrometry 化学-分析化学

CiteScore

6.20

自引率

26.50%

发文量

228

审稿时长

1.7 months

期刊介绍： Innovative research on the fundamental theory and application of spectrometric techniques.