{"title":"利用 SPR 传感器评估不同氟化玻璃纤维和拓扑绝缘体 BSTS 对皮质醇传感的影响","authors":"Fatemeh Abrishamian;Hiroyasu Sone;Kazuya Takimoto;Fua Yoshida;Musashi Nitta","doi":"10.1109/JPHOT.2024.3480249","DOIUrl":null,"url":null,"abstract":"The effects of different types of fluoride glass core fibers, from three main groups of fluorozirconate (ZrF\n<sub>4</sub>\n-based), fluoroaluminate (AlF\n<sub>3</sub>\n-based), and fluoroindate (InF\n<sub>3</sub>\n-based) fibers, were investigated in sensing salivary cortisol utilizing surface plasmon resonance (SPR) sensors. These sensors comprised multiple layers, including fluoride glass core, metal (Ag), dielectric, and dielectric grating (SiO\n<sub>2</sub>\n). The comparison was conducted to evaluate the sensor's figure of merit (FOM) and limit of detection (LOD) at 830 nm wavelength while optimizing the thickness of metal layer for different concentration of cortisol and keeping other parameters constant. The largest FOM of 20.83 RIU\n<sup>−1</sup>\n was observed for the composition of IZBSC (40 InF\n<sub>3</sub>\n-20 ZnF\n<sub>2</sub>\n-15 BaF\n<sub>2</sub>\n-20 SrF\n<sub>2</sub>\n-5 CaF\n<sub>2</sub>\n) from InF\n<sub>3</sub>\n-based group, resulting in an exceptional LOD of 0.986 fg/mL with the intensity interrogation method. This represents a tremendous advancement compared to prior reported results. Furthermore, by implementing a topological insulator Bi\n<sub>1.5</sub>\n Sb\n<sub>0.5</sub>\n Te\n<sub>1.8</sub>\n Se\n<sub>1.2</sub>\n (BSTS) into this sensor with a ZBLAN fiber for the first time, the LOD was reduced to 0.54 fg/mL, demonstrating remarkable progress in cortisol sensing capability best to our knowledge.","PeriodicalId":13204,"journal":{"name":"IEEE Photonics Journal","volume":"16 6","pages":"1-8"},"PeriodicalIF":2.1000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10716781","citationCount":"0","resultStr":"{\"title\":\"Evaluating Different Fluoride Glass Fibers and Topological Insulator BSTS Impact on Cortisol Sensing Utilizing SPR Sensor\",\"authors\":\"Fatemeh Abrishamian;Hiroyasu Sone;Kazuya Takimoto;Fua Yoshida;Musashi Nitta\",\"doi\":\"10.1109/JPHOT.2024.3480249\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The effects of different types of fluoride glass core fibers, from three main groups of fluorozirconate (ZrF\\n<sub>4</sub>\\n-based), fluoroaluminate (AlF\\n<sub>3</sub>\\n-based), and fluoroindate (InF\\n<sub>3</sub>\\n-based) fibers, were investigated in sensing salivary cortisol utilizing surface plasmon resonance (SPR) sensors. These sensors comprised multiple layers, including fluoride glass core, metal (Ag), dielectric, and dielectric grating (SiO\\n<sub>2</sub>\\n). The comparison was conducted to evaluate the sensor's figure of merit (FOM) and limit of detection (LOD) at 830 nm wavelength while optimizing the thickness of metal layer for different concentration of cortisol and keeping other parameters constant. The largest FOM of 20.83 RIU\\n<sup>−1</sup>\\n was observed for the composition of IZBSC (40 InF\\n<sub>3</sub>\\n-20 ZnF\\n<sub>2</sub>\\n-15 BaF\\n<sub>2</sub>\\n-20 SrF\\n<sub>2</sub>\\n-5 CaF\\n<sub>2</sub>\\n) from InF\\n<sub>3</sub>\\n-based group, resulting in an exceptional LOD of 0.986 fg/mL with the intensity interrogation method. This represents a tremendous advancement compared to prior reported results. Furthermore, by implementing a topological insulator Bi\\n<sub>1.5</sub>\\n Sb\\n<sub>0.5</sub>\\n Te\\n<sub>1.8</sub>\\n Se\\n<sub>1.2</sub>\\n (BSTS) into this sensor with a ZBLAN fiber for the first time, the LOD was reduced to 0.54 fg/mL, demonstrating remarkable progress in cortisol sensing capability best to our knowledge.\",\"PeriodicalId\":13204,\"journal\":{\"name\":\"IEEE Photonics Journal\",\"volume\":\"16 6\",\"pages\":\"1-8\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10716781\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Photonics Journal\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://ieeexplore.ieee.org/document/10716781/\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Photonics Journal","FirstCategoryId":"5","ListUrlMain":"https://ieeexplore.ieee.org/document/10716781/","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
Evaluating Different Fluoride Glass Fibers and Topological Insulator BSTS Impact on Cortisol Sensing Utilizing SPR Sensor
The effects of different types of fluoride glass core fibers, from three main groups of fluorozirconate (ZrF
4
-based), fluoroaluminate (AlF
3
-based), and fluoroindate (InF
3
-based) fibers, were investigated in sensing salivary cortisol utilizing surface plasmon resonance (SPR) sensors. These sensors comprised multiple layers, including fluoride glass core, metal (Ag), dielectric, and dielectric grating (SiO
2
). The comparison was conducted to evaluate the sensor's figure of merit (FOM) and limit of detection (LOD) at 830 nm wavelength while optimizing the thickness of metal layer for different concentration of cortisol and keeping other parameters constant. The largest FOM of 20.83 RIU
−1
was observed for the composition of IZBSC (40 InF
3
-20 ZnF
2
-15 BaF
2
-20 SrF
2
-5 CaF
2
) from InF
3
-based group, resulting in an exceptional LOD of 0.986 fg/mL with the intensity interrogation method. This represents a tremendous advancement compared to prior reported results. Furthermore, by implementing a topological insulator Bi
1.5
Sb
0.5
Te
1.8
Se
1.2
(BSTS) into this sensor with a ZBLAN fiber for the first time, the LOD was reduced to 0.54 fg/mL, demonstrating remarkable progress in cortisol sensing capability best to our knowledge.
期刊介绍:
Breakthroughs in the generation of light and in its control and utilization have given rise to the field of Photonics, a rapidly expanding area of science and technology with major technological and economic impact. Photonics integrates quantum electronics and optics to accelerate progress in the generation of novel photon sources and in their utilization in emerging applications at the micro and nano scales spanning from the far-infrared/THz to the x-ray region of the electromagnetic spectrum. IEEE Photonics Journal is an online-only journal dedicated to the rapid disclosure of top-quality peer-reviewed research at the forefront of all areas of photonics. Contributions addressing issues ranging from fundamental understanding to emerging technologies and applications are within the scope of the Journal. The Journal includes topics in: Photon sources from far infrared to X-rays, Photonics materials and engineered photonic structures, Integrated optics and optoelectronic, Ultrafast, attosecond, high field and short wavelength photonics, Biophotonics, including DNA photonics, Nanophotonics, Magnetophotonics, Fundamentals of light propagation and interaction; nonlinear effects, Optical data storage, Fiber optics and optical communications devices, systems, and technologies, Micro Opto Electro Mechanical Systems (MOEMS), Microwave photonics, Optical Sensors.