巴西帕金森病患者接受丘脑下核深部脑刺激治疗后出现的抑郁症状:一项横断面研究。

IF 1.4 4区 心理学 Q4 CLINICAL NEUROLOGY
Thayná Laís de Souza Arten, Amer Cavalheiro Hamdan
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引用次数: 0

摘要

帕金森病(PD)是一种主要影响运动的神经系统疾病,通常伴有抑郁症状。眼下核(STN)深部脑刺激(DBS)已成为帕金森病的一种治疗干预手段,但它对抑郁症状的影响仍然很复杂。本研究调查了帕金森病、DBS 和抑郁症状之间的关系,重点关注 DBS 如何影响巴西帕金森病患者的认知功能和情绪。该研究涉及两个队列:一个队列于 2019 年进行,有 46 名参与者;另一个队列于 2022 年进行,有 31 名患者。研究采用了不同的评估工具,包括老年抑郁量表-15 和贝克抑郁量表-II,以评估抑郁症状。结果显示,参与者的性别与是否接受 DBS 治疗之间没有明显的相关性,但在年龄、病程和日常生活活动评分方面却存在很大差异。与仅接受药物治疗的患者相比,接受 DBS 治疗的患者认知能力明显较差。此外,在其中一个队列中,使用 DBS 与抑郁症状量表评分较高有关。这些发现强调了帕金森病、DBS治疗和抑郁症状之间错综复杂的相互作用,突出了为患者提供量身定制的治疗方法的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depressive symptoms in Brazilian Parkinson's disease patients treated with subthalamic nucleus deep brain stimulation: A Cross-Sectional study.

Parkinson's disease (PD) is a neurological disorder that primarily affects movement and is often accompanied by depressive symptoms. Subthalamic nucleus (STN) deep brain stimulation (DBS) has emerged as a therapeutic intervention for PD, although its impact on depressive symptoms remains complex. This study investigates the relationship between PD, DBS, and depressive symptoms, focusing on how DBS influences cognitive function and mood among PD patients in Brazil. The study involved two cohorts: one in 2019 with 46 participants and another in 2022 with 31 patients. Distinct assessment instruments, including the Geriatric Depression Scale-15 and Beck Depression Inventory-II, were employed to evaluate depressive symptoms. The results revealed no significant correlation between participants' gender and the presence of DBS, but substantial differences were observed in age, disease duration, and Activities of Daily Living scores. Patients undergoing DBS showed notably poorer cognitive performance compared to those treated solely with medication. Furthermore, the use of DBS was associated with higher scores on depressive symptoms scales within one of the cohorts. These findings underscore the intricate interplay among PD, DBS treatment, and depressive symptoms, highlighting the necessity for tailored approaches to patient care.

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来源期刊
Applied Neuropsychology-Adult
Applied Neuropsychology-Adult CLINICAL NEUROLOGY-PSYCHOLOGY
CiteScore
4.50
自引率
11.80%
发文量
134
期刊介绍: pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.
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