通讯:瑞典北部首次发生静脉血栓后的癌症发病率和死亡率。

IF 2.6 4区 医学 Q2 HEMATOLOGY
Minh-Hoang Tran, Kim-Huong Truong-Nguyen
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引用次数: 0

摘要

我们祝贺 Hägg 等人对首次发生静脉血栓栓塞(VTE)后的癌症发病率和死亡率进行的研究,该研究为将 VTE 作为潜在恶性肿瘤的潜在标志物提供了宝贵的见解。然而,我们强调了健康用户偏倚、随访时间不明确以及统计分析调整不一致等问题。我们还建议使用 Fine-Gray subdistribution 危险模型来解决竞争风险问题,并准确报告性别术语。最后,我们建议在没有 VTE 前数据作为对比的情况下,谨慎得出首次发生 VTE 后癌症发病率高的结论,并建议在解释 VTE 诊断后 6 个月内癌症检出率较高的情况时承认潜在的监测偏差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correspondence: Cancer incidence and mortality after a first-ever venous thrombosis in northern Sweden.

We congratulate Hägg et al. on their study investigating cancer incidence and mortality following first-ever venous thromboembolism (VTE), which provides valuable insights into VTE as a potential marker for underlying malignancies. However, we highlight concerns regarding healthy user bias, the unclear follow-up duration, and inconsistent adjustment in the statistical analysis. We also suggest the use of the Fine-Gray subdistribution hazard model to address competing risks, and the accurate reporting of sex-gender terminology. Lastly, we advise caution in concluding a high incidence of cancer following first-ever VTE without pre-VTE data for comparison and recommend acknowledging potential surveillance bias when interpreting the higher cancer detection rate within 6 months of VTE diagnosis.

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来源期刊
Thrombosis Journal
Thrombosis Journal Medicine-Hematology
CiteScore
3.80
自引率
3.20%
发文量
69
审稿时长
16 weeks
期刊介绍: Thrombosis Journal is an open-access journal that publishes original articles on aspects of clinical and basic research, new methodology, case reports and reviews in the areas of thrombosis. Topics of particular interest include the diagnosis of arterial and venous thrombosis, new antithrombotic treatments, new developments in the understanding, diagnosis and treatments of atherosclerotic vessel disease, relations between haemostasis and vascular disease, hypertension, diabetes, immunology and obesity.
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