微生物群与认知障碍：当前挑战与未来展望。

IF 3.4 3区医学 Q2 NEUROSCIENCES

Journal of Alzheimer's Disease Pub Date : 2024-11-01 Epub Date: 2024-11-03 DOI:10.1177/13872877241289057

Guillaume Chapelet, Wendy Noble, Pascal Derkinderen

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引用次数: 0

摘要

最近的研究表明，肠道微生物群可能在认知功能中起着至关重要的作用。认知障碍患者的肠道有益菌往往较少，微生物多样性也较低。因此，肠道微生物群可能是认知脆弱性的潜在生物标志物。要了解影响微生物群组成和认知健康的机制和生活方式因素，还需要进一步的研究。虽然微生物群和饮食对认知障碍的直接影响仍未得到证实，但这一领域有望开发出新的预防和治疗策略。

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Microbiota and cognitive impairment: Current challenges and future perspectives.

Recent studies indicate that gut microbiota may play a crucial role in cognitive function. Individuals with cognitive impairment tend to have fewer beneficial gut bacteria and lower microbial diversity. Therefore, gut microbiota could be a potential biomarker for cognitive vulnerability. Further research is needed to understand the mechanisms and lifestyle factors affecting both microbiota composition and cognitive health. While the direct impact of microbiota and diet on cognitive impairment remains unconfirmed, this area holds promise for developing new preventive and treatment strategies.

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来源期刊

Journal of Alzheimer's Disease 医学-神经科学

CiteScore

6.40

自引率

7.50%

发文量

1327

审稿时长

2 months

期刊介绍： The Journal of Alzheimer''s Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer''s disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer''s disease.