Septimiu Murgu, Blanca Urrutia-Royo, Prince Ntiamoah, Hervé Dutau
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There is evidence and growing interest in intralesional corticosteroid injection in treating inflammation and potentially preventing recurrence. Airway specialists from distinct disciplines use different laser types, dilating balloons and anesthesia methods to manage benign CAO. Recent studies have demonstrated substantial improvements in patient breathlessness and quality of life following therapeutic airway interventions, highlighting the evolving landscape in this cross-disciplinary field.</p><p><strong>Summary: </strong>Nonmalignant CAO, arising from various mechanical, inflammatory, and infectious etiologies, poses significant morbidity and mortality risks. Current treatments include endoscopic resection, dilation, stent placement, and surgical resection which are selected based on lesion's complexity, extent, operability and patient's symptoms and goals. 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引用次数: 0
摘要
审查目的:组织学良性中央气道阻塞(CAO)的治疗非常复杂。已发表的研究主要集中于特定专科提供的诊断方法和治疗方案,但尚未关注该疾病的多学科管理。我们的目的是从耳鼻喉科、胸外科和介入性支气管镜医生参与的多学科角度,回顾目前治疗非恶性 CAO 的诊断和治疗方法:最近的研究结果:对于良性气道狭窄,可通过药物和内窥镜疗法进行治疗,手术切除仅限于复杂和复发性狭窄。有证据表明,局部注射皮质类固醇可治疗炎症,并有可能预防复发,这种疗法也越来越受到关注。不同学科的气道专家使用不同类型的激光、扩张球囊和麻醉方法来治疗良性 CAO。摘要:非恶性 CAO 由各种机械性、炎症性和感染性病因引起,具有显著的发病率和死亡率风险。目前的治疗方法包括内窥镜切除术、扩张术、支架置入术和手术切除术,根据病变的复杂程度、范围、可操作性以及患者的症状和目标进行选择。多模式和多学科的患者护理方法可提供最佳疗效。
Multidisciplinary care in nonmalignant central airway obstruction.
Purpose of review: The management of histologically benign central airway obstruction (CAO) is complex. Published studies have focused on the diagnostic approaches and therapeutic options provided by specific specialties, but there has been no focus on multidisciplinary management of this disease. Our objective is to review the current diagnostic and therapeutic modalities available for managing nonmalignant CAO from a multidisciplinary perspective involving otolaryngology, thoracic surgery and interventional bronchoscopists.
Recent findings: For benign airway strictures, management is via medical and endoscopic therapy with surgical resection reserved for complex and recurrent stenoses. There is evidence and growing interest in intralesional corticosteroid injection in treating inflammation and potentially preventing recurrence. Airway specialists from distinct disciplines use different laser types, dilating balloons and anesthesia methods to manage benign CAO. Recent studies have demonstrated substantial improvements in patient breathlessness and quality of life following therapeutic airway interventions, highlighting the evolving landscape in this cross-disciplinary field.
Summary: Nonmalignant CAO, arising from various mechanical, inflammatory, and infectious etiologies, poses significant morbidity and mortality risks. Current treatments include endoscopic resection, dilation, stent placement, and surgical resection which are selected based on lesion's complexity, extent, operability and patient's symptoms and goals. A multimodal and multidisciplinary approach to patient care could offer the best outcomes.
期刊介绍:
Current Opinion in Pulmonary Medicine is a highly regarded journal offering insightful editorials and on-the-mark invited reviews, covering key subjects such as asthma; cystic fibrosis; infectious diseases; diseases of the pleura; and sleep and respiratory neurobiology. Published bimonthly, each issue of Current Opinion in Pulmonary Medicine introduces world renowned guest editors and internationally recognized academics within the pulmonary field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.